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Effects of Comprehensive Nursing Intervention on Depression of Post-stroke Patients

Li Guilin,Fei Jingxia,Leng Wenjuan,et al.Wuxi Mental Health Center,Nanjing Medical College,Wuxi 214151,P.R.China  
Objective To explore the effects of comprehensive nursing intervention combined sertraline on depression of post-stroke patients.Methods A total of 121 post-stroke patients with depression were randomly divided into the study group(n=61)and control group(n=60).The study group patients were got the comprehensive nursing intervention combined sertraline and control group took sertraline.There were respectively evaluation of the efficacy of the two groups of patients using the Hamilton Depression Rating Scale(HAMD),the Mini-Mental state Examination(MMSE),clinical neurological lack of Dayton scale(CSS),Barthel index(MBI),before comprehensive nursing intervention and after comprehensive nursing intervention 8 weeks.Results After eight weeks,there were significant differences in HAMD,MMSE,CSS and MBI scores in the study group(tHAMD=11.9050,tMMSE=-5.5822,tCSS=12.6566,tMBI=-17.9000,Pall0.001).there were also significant differences in the control group(tHAMD=8.6587,P0.001;tMMSE=-2.8570,P0.01;tCSS=2.2251,P0.05;tMBI=-2.1007,P0.05).Before the comprehensive nursing intervention,both groups of HAMD,MMSE,the CSS,MBI scores were no significant difference(P0.05),but there were significant differences in HAMD,MMSE,CSS,and MBI scores between two groups after eight weeks(tHAMD=2.1274,P0.05;tMMSE=4.2260,P0.01;tCSS=9.1274,P0.001;tMBI=16.2776,P0.001).Conclusion Comprehensive nursing intervention combined sertraline has higher effect on post-stroke patients with depression;and can improve cognitive ability,nerves function,activity of daily living and quality of life.
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