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《Journal of Jilin Agricultural University》 1988-01
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EXPERIMENT OF LONG TERM POISONOUSNESS OF NATURAL PIGMENT-ANTHOSIANINE TO THE EXPERIMENTAL ANIMAL OF WHITE RATS

Guan Tianying  
The long-term poisonousness of natural pigment-Anthosianine to the experimental animal of white rats is observed and determined by using the way of administering medicine to the rats for 120 days, the observation of the changes in the behavior, temperature, weight, the physiological and biochemical indexes of the white rats, and the change of tissue organs with naked eyes and the histological change is made. The observation of the safety and poisonousness, side effect that may be produced by Anthosianine to the animal is also made. Then the observation of the normal quantity of natural pigment-Anthosianine (36mg of the original Anthosianine/kg per poll daily) and the effect after using twenty times and forty times of normal quantity is made. The determination of the physiological index of blood in every group of animals; the serum tran-saminase and liver function; the content of serum urea nitrogen is made. The observation of the change of visera with naked eyes and the histolo-gical change. The safety and availability of natural pigment-Antho sianine are objectively evaluated by the determination on LD50 (LD50 is 11564.3173mg/kg) and various indexes to provide the scientific evidence for the use of Anthosianine as food additive pigment.
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【References】
Chinese Journal Full-text Database 1 Hits
1 LIN Yan-chun~1, MA Hong-xia~1, ZHANG Yan-jing~2, GUAN Tian-ying~1, ZHAO Guo-liang~3(1. College of Animal Science and Technology, Jilin Agricultural University, Changehun, Jilin 130118,China; 2. College of Manage, Jilin Agricultural University, Changchun, Jilin 130118, China;3. Farming Bureau of Shuang Yang , Changchun City, Changchun, Jilin 130600, China);Subchronic Toxicity Studies of Yan-Ke-Ting Oral Liquid in Rats[J];吉林农业大学学报;2003-06
【Co-references】
Chinese Journal Full-text Database 2 Hits
1 CHENG Pei ying 1 , YU Shou ping 1, JIA Dong shu 2, CHEN Shao hui 1, YANG Xiao bing 3 (1 College of Animal Science and Technology, Jilin Agricultural University, Changchun, Jilin 130118, China; 2 Department of Guartermater Engineering,;Subchronic Toxicity Test of Compound Zengrongji in Rats[J];吉林农业大学学报;2001-03
2 Guan Tianying;EXPERIMENT OF LONG TERM POISONOUSNESS OF NATURAL PIGMENT-ANTHOSIANINE TO THE EXPERIMENTAL ANIMAL OF WHITE RATS[J];吉林农业大学学报;1988-01
【Secondary References】
Chinese Journal Full-text Database 1 Hits
1 REN Zuo-bao1,WU Run1,CUI Ying2,LIANG Jian-ping2,WANG Xuan-hui3(1.College of Veterinary Medicine,Gansu Agricultural University,Lanzhou 730070,China;2.Lanzhou Institute of Animal and Veterinary Pharmaceutics Sciences,Chinese Academy of Agricultural Sciences,Key Laboratory of New Animal Medicine Project,Ministry of Agriculture,Lanzhou 730050,China;3.Gansu Polytechnic College of Animal Husbandry Engineering,Wuwei 733006,China);Subacute toxicity tests of the NAS complex preparation in rats[J];甘肃农业大学学报;2007-06
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