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Comparative efficacy of ticlopidine and aspirin on inhibition of platelet aggregation

Xu Jun; Gao Zhiqiang; Zhou Chunnin; et al(Department of Cardiology,Jinling Hospital Nanjing,210002)  
Platelet aggregation induced by ADP was assessed to compare the efficacy of ticlopidine and aspirin.16 cases of hypertension,12 of coronary artery disease and 10 of cerebral ischemic disease were 1ncluded in two groups,Platelet aggregation was reduced from 69.70±16.07%to 28.15±17.89%afterfour weeks administration of ticlopidine,in aspirin group from 70.43±18.46%to 61.41±20.84%。No serious side effects were observed in both groups,It is conclued that ticlopidine has remarkable efficacy on the inhibition of platelet aggregation.
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