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The adhesion of pacemaker skin wounds with Histoacryl tissue adhesive: an analysis of its efficacy and cost

ZHOU Yong, JIANG Hai-bin, QIN Yong-wen, CHEN Shao-ping. Department of Cardiology, Changhai Hospital, Second Military Medical University, Shanghai 200433, China  
Objective To evaluate the clinical efficacy and cost of Histoacryl tissue adhesive in adhering the pacemaker skin wounds. Methods During the period from April 2010 to October 2010, permanent cardiac pacemaker implantation was performed in 112 patients in authors' hospital. The patients were divided into tissue adhesive group (n = 64) and conventional suture group (re = 48). Histoacryl tissue adhesive was employed in patients of tissue adhesive group. The extent of wound healing, the post-procedure hospitalization days and the hospitalization cost were recorded, and the results were compared between the two groups. Results The clinical baselines of the two groups were compatible with each other. Primary closure of wounds was achieved in all patients of two groups. The mean post-procedure hospitalization time in tissue adhesive group and in conventional suture group was (4.4 ±1.4) days and (6.2 ±1.3) days respectively, the difference between the two groups was statistically significant (P 0.01). If the costs of pacemaker equipment, surgery and DSA were not included, the mean medical expenses in tissue adhesive group and in conventional suture group were (4 383.39 ± 792.40) and (4 199.81 ± 1059.93) Chinese yuan respectively, and no significant difference in medical expenses existed between the two groups (P = 0.651). Conclusion Histoacryl tissue adhesive can effectively adhere pacemaker wounds tissue. Compared to the use of conventional suture, the use of Histoacryl tissue adhesive can reduce the post-procedure hospitalization days although the medical expenses are quite the same as that using conventional suture treatment. (J Intervent Radiol, 2011, 20: 655-656)
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