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《Mycosystema》 2018-10
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A general review of study on mixed fungal infection in AIDS patients

YANG Xin-Yu;LI Ruo-Yu;LIU Wei;Department of Dermatology, Peking University First Hospital, Research Center for Medical Mycology, Beijng Key Laboratory of Molecular Diagnosis on Dermatoses, Peking University;  
Fungal infection is the most common opportunistic infection in acquired immune deficiency syndrome(AIDS) patients and is one of the most important causes of death. Common opportunistic fungal infections include candidiasis, pneumocystosis, cryptococcosis, Talaromyces marneffei infection, histoplasmosis, and coccidioidomycosis. This paper introduces the relationship between CD4~+T lymphocytes and opportunistic fungal infections and the epidemiology, pathogenesis, clinical manifestation, diagnosis, treatments and prevention of common fungal infections in AIDS patients. These knowledges are of great significance for clinicians to improve their understanding of the diseases and to make early diagnosis, to treat early, to select antifungal drugs reasonably, and to improve the quality of life and prolong the survival time of patients.
【Fund】: 国家自然科学基金(81471925 81671990)~~
【CateGory Index】: R512.91;R519
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