Recent advances in animal model experimentation in Talaromyces marneffei infection research
HE Li-Ya;HUANG Xiao-Wen;LIU Ying-Hui;CHEN Zhi-Wen;XI Li-Yan;Department of Dermatology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University;Department of Dermatology, Guangdong Provincial Hospital of Traditional Chinese Medicine;Dermatology Hospital of Southern Medical University;
Talaromyces marneffei, formerly known as Penicillium marneffei, is a significant emerging pathogenic fungus in Southeast Asia which can cause life-threatening systemic infection. Most infections occurred in individuals with Human Immunodeficiency Virus(HIV), and the primarily reason for the increase in the number of cases is HIV pandemic. The pathogenesis of infection due to T. marneffei is unclear. Researchers often use animals for disease model studies to provide strong evidence for the pathogenesis and clinical treatment of the disease. This review summarizes the research on animal models of T. marneffei infection in recent years.
【CateGory Index】： R519;R-332