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《Acta Academiae Medicinae Jiangxi》 2001-01
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Protective Effects of Ginsenosides on Cardiomyocytes Injured by Ischemia-Reperfusion

CHEN Tu-gang, LUO Wei, CHENG Xiao-shu (Department of Cardiology, the Second Affiliated Hospital, Jiangxi Medical College, Nanchang 330006,China)  
The purpose of this study was to investigate the relationship of ischemia/reperfusion (I/R) injury and cell apoptosis, and to evaluate the protective effects of various concentration ginsenosides (GS) on ischemia/reperfusion model of cultured cardiomyocytes in vitro by detecting the cell necrosis and cell apoptosis. Results: (1) GS had no significant effect on the normally cultured cardiomyocytes. (2) I/R injury could cause cardiomyocytes apoptosis but ischemia injury could not. (3) GS had significant protective effects on both necrosis and apoptosis induced by I/R injury, and the protective effects were positive correlation to the levels of GS (0~160 mg/L).
【CateGory Index】: R285.5
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【References】
Chinese Journal Full-text Database 5 Hits
1 LU Juan;HU Jihong;School of Publish Health, Gansu College of Traditional Chinese Medicine;;Research progress of the intervention of traditional Chinese medicine in vitro on the differentiation of mesenchymal stem cells to myocardial cells[J];China Medicine and Pharmacy;2014-04
2 ;Traditional Chinese Medicine and Culture of Cardiac Muscle Cells[J];Guiding Journal of TCM;2007-04
3 WANG Zhaohui, XIAN Shaoxiang, YANG Zhongqi, LI Nanyi, ZHAO Licheng (Doctoral Graduate of Grade 2003, Guangzhou University of TCM, Guangzhou 510405, China; The First Affiliated Hospital of Guangzhou University of TCM, Guangzhou 510405, China);Inductive Effect of Ginsenosides on Differentiation of Rat Marrow Mesenchymal Stem Cells into Myocardial Cells in Vitro[J];Journal of Guangzhou University of Traditional Chinese Medicine;2006-02
4 WANG Jie1,ZHANG Jin-sheng2(1.Guanganmen Hospital of China Academy of Chinese Medical Sciences,Beijing 100053,China;2.First Affiliated Hospital of Henan College of TCM,Zhengzhou 450000,Henan,China);Effect of Study the Stem Cells to the Development of TCM Theory[J];Chinese Archives of Traditional Chinese Medicine;2007-06
5 Gu Wanli,Shi Zaixiang China-Japan Fredship Hospital(Beijing 100029));The Non-circulatory Mechanism of Traditional Chinese Herbs in Protecting Myocardial Ischemic Injury[J];Chinese Journal of Integrative Medicine on Cardio-/Cerebrovascular Disease;2005-05
【Co-citations】
Chinese Journal Full-text Database 8 Hits
1 Wu XM, Jiang ZL,Jin SY,et al (Institute of Nautical Medicine,Nantong Medical College 226001);EFFECTS OF COMPOUND PANAX GINSENG EXTRACTS AGAINST ANOXIC CEREBRAL INJURY[J];Medical Journal of Communications;1999-01
2 Pan Qiangwen, et al Department of Physiology, Luzhou Medical College;EFFECTS OF PANAXADIOL SAPONINS ON PROLIFERATION OF HUMAN RENAL TUBULAR CELL[J];Journal of Luzhou Medical College;2001-02
3 GU Jianlan, 1SHI Zhongyuan,WU Xiaomei,et al (Institute of Nautical Medicine,Nantong Medical College,Nantong 226001, 1Shanghai Jiao tong University);Protective effect of gingsen and EGb mixture on elevation 8000m hypoxia rats[J];Journal of Nantong Medical;2003-04
4 ;人参总皂甙的耐缺氧效应机理研究[J];Food Science;2002-08
5 ZHU Li, SHI Zhong-Yuan1, WU Xiao-Mei, ZHANG Zhi-Jun, JIN Shu-Yi Institute of Nautical Medicine, Nantong Medicine College, Nantong 226001, Jiangsu, China; 1 Institute of Ocean Underwater Engineering, Shanghai 200231,China;Effects of ginseng and EGb mixture on acute hypoxia injury in rat brain[J];Chinese Journal of Clinical Pharmacology and Therapeutics;2004-09
6 JIANG Zhenglin, WU Xinmin, CHEN Yun, et al. Institute of Nautical Medicine, Nantong Medical College, Nantong Jiangsu, 226001;Effects of ginsenosides against anoxic injury in rat brain[J];;2000-01
7 MENG Zhuang-zhi,BI Fu-long,LI Jian-guo(Department of Human Anatomy,Inner Mongolia University of Nationalities,Tongliao 028041,Innor Mangolia,China);Effect of Ginsenosides on Ischemia Reperfusion Injury of Skeletal Muscle And Morphologic Study[J];Chinese Archives of Traditional Chinese Medicine;2009-05
8 YIN Dongfeng1 Dilixiati.Baikeli1 ZHAO Linwen2 1.Department of Pharmacy,Urumqi General Hospital of Lanzhou Military Region of PLA,Xinjiang Uygur Autonomous Region,Urumqi 830000,China;2.Department of Pharmacy,Nileke County People ′s Hospital,Xinjiang Uygur Autonomous Region,Nileke 835700,China;Effects of the compound shuangshen on hypoxia tolerance of mice[J];China Medical Herald;2013-22
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 Han Mingxiang;Discussion on the Pathogenesis of Cardiac Functional Insufficiency[J];Journal of Anhui Traditional Chinese Medical College;1988-02
2 Han Mingxiang et al;Clinical Study on Treatment of Heart-Qi Deficiency and Heart-Yin Deficiency in Coronary Disease with Ginseng Injection[J];Journal of Anhui Traditional Chinese Medical College;1993-04
3 Xu Hongmei,Liu Qingyun,Dai Min,Peng Daiyin,Zi Xiaomei (Department of Pharmacy,Anhui College of TCM,Hefei 230038,China);THE EFFECT OF ANTI-THROMBUS ON TOTAL GLUCOSIDES OF CHISHAO[J];JOURNAL OF ANHUI TRADITIONAL CHINESE MEDICAL COLLEGE;2000-01
4 NIE Song liu,XU Xian xiang,XIA Lun zhu (Hospital of Lu′an City,Anhui Lu′an 237000,China);EFFECT OF TOTAL SAPONINS OF CODONOPSIS ON BLOOD LIPID AND NITRIC OXIDE LEVEL IN EXPERIMENTAL HYPERLIPEMIA RATS[J];Journal of Anhui Traditional Chinese Medical College;2002-04
5 ZENG Xiao li*, TU Zhi guangDepartment of Clinical Biochemistry in Chongqing University of Medical Sciences, Chongqing 400016, P R China;Total saponins of panax ginseng reverse some plasmo phenotypesin human hepatoma cell line[J];CHINESE JOURNAL OF CANCER;2000-08
6 HU Dai ju,MA Jun,ZHAO Jing jing,ZHAO Xiao kang,LI Qing,WANG Bei bei (Faculty of Clinical Medicine,Bengbu Medical College,Anhui 233003,China);Protective effect of Shenmai injection on pituitrin-induced myocardial ischemic injury in mice[J];Journal of Bengbu Medical College;2004-03
7 Liu Sai,Su Dongmei,Wang Chunbo,  et al Department of Pharmacology, Qingdao Medical College,Qingdao 266021;EFFECT OF TOTAL FLAVONE IN RADIX PUERARIAE ON THE ISOLATED THORACAORTIC STRIPS IN RABBIT[J];;1998-03
8 Zhan Hongsheng Zhejiang College of TCM,Hangzhou(310009);Experimental Method of Medicinal Serum and Its Application Prospects in the Study and Making of New Chinese Drugs[J];JOURNAL OF ZHEJIANG COLLEGE OF TCM;2000-02
9 Xu Chengshui(徐承水) Department of Biology,Qufu Normal University,Shandong Qufu(273165);Effects of The Lycium Chinese Mill.(LcM.)on The Endurance Capacity of Mice[J];JOURNAL OF ZHEJIANG COLLEGE OF TCM;2000-04
10 Gao Chengxian,Ding Zhishan,Wo Xingde,et al Zhijing College of TCM,Hangzhou(310053);Exper imental Study of Xufu Zhuyu Tang on Anti myocardial lschemia and Hypoxia Tolerance[J];Journal of Zhejiang College of Tcm;2001-02
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 LU Juan;HU Jihong;School of Publish Health, Gansu College of Traditional Chinese Medicine;;Research progress of the intervention of traditional Chinese medicine in vitro on the differentiation of mesenchymal stem cells to myocardial cells[J];China Medicine and Pharmacy;2014-04
2 LI Yu-bing,HUANG Zheng-de(TCM University of Hunan,Changsha,Hunan,410208,China);Progress of intervention mechanism of Chinese medicine on cardiovascular diseases treated with stem cell transplantation[J];Journal of Traditional Chinese Medicine University of Hunan;2011-07
3 HAN Man,MA Li,YU Yuan-wang.Department of Physiology and Department of Anatomy,Shaanxi University of Chinese Medicine,Xianyang 712046,China;Effects of Shenfu Xiongze Decoction on cardiac function of adriamycin-induced heart failure rats[J];Global Traditional Chinese Medicine;2012-05
4 XIE Xi-sheng,LIU Heng-chuan,FAN Jun-ming,LI Hui-juan.Department of Nephrology,West China Hospital,Sichuan University,Chengdu 610041,China;Effects of Ginsenoside Rb1 on TGF-β1 Induced p47phox Expression and Extracellular Matrix Accumulation in Rat Renal Tubular Epethelial Cells[J];Journal of Sichuan University(Medical Science Edition);2009-01
5 HUANG Ren-bin,L Ji-hua,ZHANG Xu-dong,FU Shu-jie,JIAO Yang(School of Pharmacy,Guangxi Medical University,Nanning,Guangxi,530021 P.R.China);Effects of Yulangsan flavonoid on myocardial ischemia reperfusion injury in isolated rat hearts[J];West China Journal of Pharmaceutical Sciences;2010-03
6 Zhao Yun,Xu Da,Yi Dan,Wu Lei,Yang Zhi-hua,Qian Ling-jia(Institute of Hygiene and Environmental Medicine,Academy of Military Medical Sciences,Tianjin 300050,China);EFFECT OF CHINESE MEDICINE—LGQX ON HYPOXIA-TOLERANCE AND ISCHEMIA OF MYOCARDIUM[J];Journal of Preventive Medicine of Chinese People's Liberation Army;2007-05
7 ZHANG Jin-sheng(First Affiliated Hospital,Henan University of Traditional Chinese Medicine,Henan 450000);Connotation of dispelling stasis and producing the new in theory of activating blood and resolving stasis therapy[J];Journal of Beijing University of Traditional Chinese Medicine;2012-04
8 WANG Zhenchang,HUANG Jingjing,LIU Ming(The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine,Nanning 530021,Guangxi,China);Rougan Huaqian Granules Combined with Bone Marrow Stem Cell Transplantation on Liver Fibrosis in Rats[J];Liaoning Journal of Traditional Chinese Medicine;2013-02
9 Zhang Chunrong The Second Affiliated Hospital of Henan Technology University,Luoyang Henan China 471000;Clinical Observation of Shengui Capsule in the Treatment of End-stage Renal Disease with Heart Failure[J];China Journal of Chinese Medicine;2013-05
10 FANG Xian - ming, TANG Yao - ping, ZHENG De - jun ( The Affiliated Ruikang Hospital of Guangxi College of TCM, Nanning 530011, China);The Influence of Anxin Granules on Homotypic Cysteine of Plasma in Coronary Heart Disease[J];New Journal of Traditional Chinese Medicine;2005-03
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