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《Acta Academiae Medicinae Jiangxi》 2001-01
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The Classification in Vitro and Observations on Clinical Treatment of Aplastic Anemia

LI Hui-hui, YANG Bi-yun, LIAO Yi-xiang, XIONG Hong (Department of Haematology, the Second Affiliated Hospital of Jiangxi Medical College, Nanchang 330006,China)  
Objectives: To explore the classification in vitro by pathogenesis and to observe the clinical treatment of aplastic anemia (AA). Methods: Bone marrow mono-nucleus cells (BMMNC) were cultured in methylcellulose semisolid medium. The patients with AA, divided into different groups by random, were treated with androgen or combined androgen and cyclosporin A (CSA). Results: There were three types of BMMNC in AA patients as follows: stem cells defect, immune mediation and microenvironmental defect. Among them, the type of stem cells defect was more. The curative effect of combined androgen and CSA was better than that of androgen ( P <0.01). Conclusions: The pathogenesis of AA is different. The value of CSA in the treatment of AA is worth further studying.
【CateGory Index】: R556.5
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【References】
Chinese Journal Full-text Database 2 Hits
1 LI Hui hui,YANG Bi yun,TU Mei feng,RAO Yan fei,WU Dong sheng (Department of Haematology,the Second Affiliated Hospital of Jiangxi Medical College,Nanchang 330006,China);Study of Sensitivity Test of Cyclosporin A in Aplastic Anemia[J];Acta Academiae Medicinae Jiangxi;2002-02
2 LI Wei 1, WANG Yao-li 1, QIOU Ding-zhong 1, DU Ling-zhen 1, WU Wei-li 2, SUN Guan-lin 2 ( 1Department of Pediatrics, 2Shanghai Institute of Hematology, Ruijin Hospital, Shanghai Second Medical University, Shanghai 200025, China);Significance and Detection of Hematopoietic Progenitor Cells in Aplastic Anemia of Childhood[J];Acta Universitatis Medicinalis Secondae Shanghai;2005-02
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 Li Fanglin; Zhang Minggong; Song Suqin; et al(Dept. of Hematology, the Affiliated Hospital of Shandong Medical University);EFFECTS OF ATG AND ANTI-CD_3McAb ON GROWTH OF CFU-GM IN PATIENTS WITH AA IN VITRO[J];ACTA ACADEMIAE MEDICINAE SHANDONG;1995-04
2 HUANG Hai-wen , FU Jinxiang , ZHANG Xueguang ,et al. Department of Hematology , Second Affiliated Hospital,Soochow University,Suzhou 215004,China;Detection of soluble CD40L level in peripheral blood and bone marrow of patients with aplastic anemia[J];Jiangsu Medical Journal;2003-04
3 CHANG Yingjun, ZOU Zhenghui, CAO Xiangshan, et al Department of Hematology, The Second Affiliated Hospital, Suzhou Medical College, Suzhou 215004, China;A study on cyclosporin A sensitivity test in aplastic anemia[J];CHINESE JOURNAL OF INTERNAL MEDICINE;2000-05
4 HUANG Hai-wen, FU Jin-xiang, LI Jun, et al. No. 2 Affiliated Hospital of Soochow University, Suzhou 215004, China;sCD40L in combination with HGFs and ex vivo expansion of cord blood CD34~+ cell[J];Chinese Journal of Organ Transplantation;2005-06
5 FU Jinxiang *, YU Gehua, ZHANG Xueguang. *No.2 Affiliated Hospital of Soochow University, Suzhou 215004, P. R. China;Abnormal expressed co-stimulating factors and their relationship to activation of T lymphocytes in patients with aplastic anemia[J];Chinese Journal of Microbiology and Immunology;2002-02
6 HAN Zhao*, ZHENG Rong-yuan, LIU Hong-yu, SHEN Zhi-jian, GAO Shen-meng, YE Hao-hao, ZHANG Xu. *Department of Neurology, The First Hospital, Wenzhou Medical College, Wenzhou 325000, China;Dynamic expression of B7∶CD28/CTLA4 costimulatory molecules on peripheral blood cells in myasthenia gravis[J];Chinese Journal of Microbiology and Immunology;2003-03
7 CHEN Guibin,SHAO Zonghong,JIA Hairong,et al.Institute of Hematology and Blood Diseases Hospital,CAMS and PUMC,Tianjin 300020;In vitro proliferation and differentiation of bone marrow stem cells of aplastic anemia patients[J];CHINESE JOURNAL OF HEMATOLOGY;1999-10
8 HE Guangsheng, SHAO Zonghong, ZHANG Yizhi, et al. Institute of Hematology and Blood Diseases Hospital, CAMS and PUMC, Tianjin 300020, China;Sequential intensified immunosuppressive therapy combining with hematopoietic growth factors in the treatment of severe aplastic anemia[J];Chinese Journal of Hematology;2001-04
9 DONG Xiao-yuan, XU Cong-gao, SUN Guo-rui,ZHANG Ti,PENG Jun.Department of Hematology, Qilu Hospital of Shandong University, Jinan 250012,China Corresponding author: XU Cong-gao;Expression of three kinds of GPI-anchor proteins in paroxysmal nocturnal hemoglobinuria, aplastic anemia and myelodysplastic syndromes patients and their clinical implications[J];Chinese Journal of Hematology;2004-04
10 SHEN Rong,XU Cong-gao,LI Li-zhen,ZHANG Ti,QIN Xue-mei,LI Jie,ZHAO Chuan-li. Qilu Hospital of Shandong University,Jinan250012,China Corresponding author:XU Cong-gao;Study on the T lymphocytes early activation and soluble tumor necrosis factor receptor in patients with aplastic anemia[J];Chinese Journal of Hematology;2004-04
【Secondary References】
Chinese Journal Full-text Database 5 Hits
1 YANG Surong,LU Yingqing,YAO Minghui(Department of Pharmacology,Shanghai Medical College,Fudan University,Shanghai 200032,China);Effects of GM-CSF/IL-3 fusion protein on suppressive hematopoiesis of bone marrow caused by cyclophosphamide in rhesus monkeys[J];Chinese Journal of Clinical Pharmacy;2009-01
2 LI Hu-sheng (Department of Hematology,Red Cross Hospital of Yulin 537000,Guangxi,China);Clinical significance and culture of hematopoietic progenitor cells in aplastic anemia[J];Internal Medicine of China;2008-04
3 XU Rui-rong~1,WANG Yan~1,AN Yu-ji~1,YU Zhi-feng~2,DAI Xi-meng~2(1.Affliatied Hospital of Shandong University of TCM,Jinan 250011,China;2.Tianjin University of TCM,Tianjin 300193,China);Clinical study on treatment of chronic aplastic anemia with method of invigorating the kidney and marrow[J];Journal of Shandong University of Traditional Chinese Medicine;2006-04
4 ZHANG Hua(Department of Pediatrics,Red Cross Hospital of Yulin City,Yulin 537000,China);Clinical Significance and Culture of Hematopoietic Progenitor Cells in Children with Aplastic Anemia[J];Journal of Applied Clinical Pediatrics;2007-15
5 WANG Yan,XU Rui-Rong Affiliated Hospital,Shandong University of Traditional Chinese Medicine,Jinan 250011,Shandong Province,China;Expression of Hematopoietic Cytokines EPO,SCF and GM-CSF in Bone Marrow Cells of Patients with Chronic Aplastic Anemia[J];Journal of Experimental Hematology;2008-05
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