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《Laboratory Medicine and Clinic》 2008-15
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Analysis of drug resistance of Pseudomonas aeruginosa to commonly used antibacterial agents

WU Zhen-an. Department of Clinical Laboratory,Beijing Hospital of Integrated Traditional and Western Medicine,Beijing 100039,China  
Objective To investigate the drug resistance of Pseudomonas aeruginosa to commonly used antibacterial agents,and to provide evidence for rational use of antibacterial agents.Methods Disc agar diffusion method (Kirby-Bauer method) was applied to performing drug susceptibility test.Results The drug resistant rate of Pseudomonas aeruginosa was the lowest to imipenem followed by cefoperazone/sulbactam and amikacin (12.7%,22.8% and 30.5% respectively). The drug resistant rate of Pseudomonas aeruginosa was the highest to ampicillin followed by ampicillin/sulbactam,sulfamethoxazole/trimethoprim and cefazolin (100.0%,99.2%,97.3% and 92.3% respectively).Conclusion Clinicians should use antibiotics rationally according to the results of drug sensitive tests so as to decrease or prevent accrescence of drug resistant strains.
【CateGory Index】: R516
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【Citations】
Chinese Journal Full-text Database 1 Hits
1 CHENG Min,XU Li-ping,YANG Jing.Department of Laboratory Medicine, Central Hospital of Sichuan Forestry, Chengdu 610081,China;Research on drug resistance of Pseudomonas aeruginosa[J];Laboratory Medicine and Clinic;2007-04
【Co-citations】
Chinese Journal Full-text Database 1 Hits
1 ZHANG Feng-hua1,YUAN Hong1,XIAO Xiao-guang 1,WANG Jing 1,CHEN Jie1,JIA Yu-jie 2 (1.Department of Medical Microbiology Laboratory,the First Affiliated Hospital of Dalian Medical University,Dalian 116011,China;2.Department of Aathophysiology,Dalian Medical University,Dalian 116044,China);Three-dimensional method applied to detect beta-lactamases in imipenem-resistant pseudomonas aeruginosa[J];Journal of Dalian Medical University;2009-05
【Co-references】
Chinese Journal Full-text Database 1 Hits
1 XU Hong-tao, ZHANG Xiu-zhen. (Beijing Hospital, Beijing 100730, China);Study on the resistance mechanism of nosocomial isolates of multi-resistant Pseudomonas aeruginosa[J];Chinese Journal of Infection and Chemotherapy;2005-03
【Secondary Citations】
Chinese Journal Full-text Database 1 Hits
1 YE Hui-fen, CHEN Hui-lin, YANG Yin-mei, LI Hong-yu, SU Dan-hong, Huang Lu-xia.(The First People's Hospital of Guangzhou,Guangzhou510180,China);Surveillance of common pathogenic bacterial resistance in Guangzhou in 2003[J];Chinese Journal of Infection and Chemotherapy;2005-01
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