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《Journal of Jinzhou Medical Coilege》 1993-01
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EFFECT OF PAOA ON IL_2 PRODUCTION OF SPLENOLYMPHOCYTE OF MICE

Pan Xingyu(Departmnt of Immunology and Microbiology Jinzhou Medical College)  
This paper reports that PAOA, an extract from a traditional chinese medicinal herb, obviously inhibits IL_2 production of splenolymphocyte of mice (P0.01). The drug in concentration of 10μg/ml is most powerful for the inhibition of IL_2 production of splenolymphocyte of mice induced by Con-A (IP=116%). The drug in concentration of 100 and 1000μg/ml is also considerably powerful. But the drug in concentration of 1μg/ml dose not inhibit IL_2 production. The drug ic concentration of 1.10.100 and 1000μg/ml obviourly inhibitsIL_2 production of splenolymphocyte of mice by Con-A-and-PAOA-free method (P0.01).Among these four concentrations, 10μg/ml is also most powerful for inhibition of IL_2 production. PAOA is a traditional chinese medicinal herb used in FUZHENG-GU-BEN and YANG-YIN-RUN-ZAO therapy. The effect of PAOA on immune system has not been determined. But this experiment shows that PAOA may be a new immuno-suppressive preparation.
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【References】
Chinese Journal Full-text Database 6 Hits
1 Zhang Pei et al(Department of Microbiology,Jinzhou Medical College);SUPPRESSION OF SOPHORAMINE ON IMMUNE FUNCTION[J];JOURNAL OF JINZHOU MEDICAL COLLEGE;1996-01
2 Li Shuhua,et al(Department of Microbiology,Jinzhou Medical College);EFFECT OF PA-MSHA VACCINE COMBINED WITH S-180 TUMOR VACCINE ON PROLIFERATION OF LYMPHOCYTES AND PRODUCTION OF IL_2 IN TUMOR-BEARING MICE[J];JOURNAL OF JINZHOU MEDICAL COLLEGE;1996-06
3 Wu Xuemin,et al (Department of microbialogy,Jinzhou Medical College);THE EFFECT OF PAOA ON ERYTHROCYTE ROSETTE FOMATION OF MOUSE[J];JOURNAL OF JINZHOU MEDICAL COLLEGE;1997-01
4 Wu Xuemin,et al (Department of Microbiology);EFFECT OF PAOA ON T LYMPHOCYTE TRANSFORMATION OF MICE[J];JOURNAL OF JINZHOU MEDICAL COLLEGE;1997-03
5 Li Shuhua,et al(Department of Immunology and Microbiology);THE INFLUENCE OF PAOA—EXTRACT ON THE SURFACE MARKS OF CEM CELLS[J];JOURNAL OF JINZHOU MEDICAL COLLEGE;1997-06
6 Liu Xin;Zhou Zhengren(Department of Microbiology,School of Basic Medical Sciences,China、Medical University ,Shenyang,110001);The Effect of Berbamine on the Immunoregulation of BALB/c Mice[J];JOURNAL OF CHINA MEDICAL UNIVERSITY;1996-03
【Citations】
Chinese Journal Full-text Database 1 Hits
1 Zhu Ling Yun,et al Peking Union Medical University;STUDY OF SOME DRUGS ENHANCING L-2 PRODUCTION[J];Chinese Journal of Immunology;1988-05
【Co-citations】
Chinese Journal Full-text Database 4 Hits
1 Chen Xiaofeng Dept.of Traditional Chinese Medicine,FCTCM;Function of Biological Responses Modifiers(BRM)in TCM Prevention &.Treatment for Tumor[J];Journal of Fujian College of Traditional Chinese Medicine;1993-01
2 Wang Lunan et al(Department of Microbiology, Jinzhou Medical College);THE EFFECT OF EPIMEDIUM POLYSACCHARIDE(EPS) AND OTHERE THREE DRUGS ON HUMAN INTERLEUKINE 2(IL_2) ACTIVITY——MTT COLORIMETRIC ASSAY USING THYMOCYTES OF MICE[J];Journal of Jinzhou Medical Coilege;1990-02
3 Jin Yanshu(Department of Immunology and microbiology, Jinzhou Medical College);EFFECT OF PAOA ON MONOPHASIC AND DIPHASIC MIXED CULTURE OF MOUSE SPENOCYTE IN VITRO[J];JOURNAL OF JINZHOU MEDICAL COLLEGE;1994-01
4 Huang Zhen-yu Zhao Wei-kang Jin Guo-qin Department of Biochemistry,Shanghai University of TCM,Shanghai(200032)~*Present address:Department of Molecular Immunology and Cell Biology,Shanghai Cancer Institute,Shanghai(200032);The Effect of Guzhen Recipe (固真方) on Interleukin-2 Gene Transcription in Immunosuppressive Mice[J];Chinese Journal of Integrated Traditional and Western Medicine;1997-S1
【Co-references】
Chinese Journal Full-text Database 5 Hits
1 Jiang Xurong, First Affiliated Hospital, Dalian Medical College;INDUCTION OF DIFFERENTIATION IN THE HUMAN ERYTHROLEUKEMIA CELL LINE K562 BY GINSENOSIDES[J];;1991-04
2 Liu Xin et al;EXPERIMENTAL RESEARCH ON THE IMMUNOREGULATORY EFFECT OF KOREAN EPIMEDIUM POLYSACCHARIA[J];Journal of Jinzhou Medical Coilege;1992-02
3 Jin Yanshu(Department of Immunology and microbiology, Jinzhou Medical College);EFFECT OF PAOA ON MONOPHASIC AND DIPHASIC MIXED CULTURE OF MOUSE SPENOCYTE IN VITRO[J];JOURNAL OF JINZHOU MEDICAL COLLEGE;1994-01
4 Jin Ying;Wang Xiaodong; et al(Department of Pharmacolngy, Jinzhou Medical College, Jinzhou);Protective Effects of Sophoramine on Acute Myocardial Infarction and Reperfusion Injury in Conscious Rats[J];Chinese Traditional and Herbal Drugs;1994-07
5 Wang Huei-fen;Chang Yu-fen et al Depart of Microbiol of Hebei Med College, Shijiazhuang;A Survey of Influencing Factors on the Mouse Lymphocytes E Rosette Formation[J];Chinese Journal of Immunology;1985-01
【Secondary References】
Chinese Journal Full-text Database 7 Hits
1 GAO Xian-hui, LIU Wan-shu,et al (Jinzhou Medical College, Jinzhou 121001 China);Effect of Yoghurt on Proliferation of Splenic Cells of Mice[J];Journal of Jinzhou Medical College;2002-01
2 LV Xue-rong,PAN Xing-yu,CHEN Ying,JIN Yan-shu,TONG Wei (Department of Immunology and Microbiology, Jinzhou Medical College, Jinzhou 121001 China);The Inhibitory Effect of EB-PAOA on CEM[J];Journal of Jinzhou Medical College;2004-05
3 ZHU Can - yang. ( Hainan Provincial People' s Hospital, Haikou 570102, Hainan, P. R. China);Analysis of the pharmaceutical action of EBB.[J];China Tropical Medicine;2005-01
4 WANG Xiao-lin,ZHONG Fang-li,YANG Lei (School of Pharmaceutical Engineering and Chemistry,Jilin Institute of Chemical Technology, Jilin 132022,Jilin,China);The Extraction Process of Polysaccharide in Polygonatumodoratum(Mill.) Druce. with Microwave Extraction Method[J];Food Research and Development;2012-03
5 Liu Xin,Shen Feng,Yang Xiaolin (Department of Microbiology,Shenyang Medical College,Shenyang 110031);Effect of PLGB on Activity of Immune Cell in Mice[J];JOURNAL OF SHENYANG MEDICAL COLLEGE;1999-03
6 YUAN Zong jun (Xinyi People's Hosptial, Jiangsu 221400, China);Discussion on Clinical Selection of Chinese Anticancer Drugs[J];LiShiZhen Medicine and Materia Medica Research;2001-07
7 JIANG Zhi-lin1,BAI Ru-xia2,GUI Fu-rong1,LI Zheng-yue1,LIU Yun1(1.Key Laboratory for Agricultural Biodiversity and Pest Management of China Education Ministry,Plant Protection College,Yunnan Agricultural University,Kunming 650201,China;2.First People's Hospital of Yunnan Province,Kunming 650032,China);Research Progress on Pharmacological Effect and Utilization of Polygonatum Odoratum[J];Special Wild Economic Animal and Plant Research;2012-03
【Secondary Citations】
Chinese Journal Full-text Database 1 Hits
1 Zhang Pu,et al (Institute of Basic Medical Science, Academy of Medical Science and WHO Collaborating Center for Research and Training in Immnoulogy Beijing);Condition for IL-2 production and comparison of different method testing IL-2[J];Chinese Journal of Immunology;1986-06
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