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《Journal of Liaoning Medical University》 2007-01
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Effect of Manganese on Cardiomyopathy of Diabetic Rats

KANG Yan-ping,WANG Guo-qiu,QI Zhi-min,LI Shu-yun (Liaoning Medical University,Jinzhou 121001 China)  
Objective This paper is to lbserve the protecting roles of Manganese on myocardium of Ⅱ diabetic rat and to explore their mechanisms.Methods Experimental animals were divided in to three groups: the control group,the diabetic group and the Manganese supplied groups.The blood sugar level of each group was deteted when the rats had been fed for 4 weeks,6 weeks,10 weeks and 14 weeks.We duplicated diabetic rat pattern in 8 weeks and measured MDA content of myocardium tissue and Mn-SOD activities and retained myocardium tissue to make electron microscope observation.Results Compared with that of the diabetic group,MDA content of myocardium tissue Manganese supplied group significantly decreased,but Mn-SOD activities greatly increasod.Through pathological examination,it was found that Manganese supplied group had less inner root of tunica intima of myocardial micro-vessel and smaller basilar membrane thickness than the diabetic groups.Conclusions Manganese supplement,which is related to the acceleration of anti-oxidation action,can help recover myocardial injury of Ⅱ diabetes.
【CateGory Index】: R587.1
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Chinese Journal Full-text Database 1 Hits
1 TANG Hongpeng,WANG Jintao,LIN Hongjin,XU Shiwen (College of Veterinary Medicine,Northeast Agricultural University,Harbin,Heilongjiang 150030);Effect of Subchronic Manganism on Liver in Cocks[J];China Poultry;2009-19
Chinese Journal Full-text Database 4 Hits
1 WT5”BX]GUO Xiaohua,LU Zhihong,LI Hen,ZHU jiaming,LI Leishi Research Institute of Nephrology,Jinling Hospital,Nanjing University Clinical School of Medicine,Nanjing 210002;A NOVEL RAT MODEL OF TYPE 2 DIABETES MELLITUS[J];CHINESE JOURNAL OF NEPHROLOGY, DIALYSIS & TRANSPLANTATION;2000-04
2 Wang Huiwen Wang Fengzhi Zhong Jianhua (Department of Epidemiology,Shenyang Medical College Shen Yang 110031) Keywords diabetes;mellitus;calcium;magnesium;manganese;Research on the Relation Between Calcium,Magnesium,Manganese and Diabetes Mellitus[J];STUDIES OF TRACE ELEMENTS AND HEALTH;1997-03
3 LEI Ming 1, LIU Xin-qiu 2, XING Feng-you 2 (? 1?The Second Hospital, Jiamusi University,? 2?Department of Physiology, Basic Medical College Jiamusi University,Jiamusi 154002,China);Changes of ultrastructure and level of nitric oxide in the myocardium of rats with experimental non-insulin-dependent diabetes mellitus[J];Chinese Journal of Pathophysiology;2002-04
4 Jiang Jia - Hua, . Xiong Ai - Hua, Zhong, Ling . Department of Pharmacology, Jinan University Medical .College. Guangzhou( 51O632) , .;^Changes of MDA content and SOD and N+ - K+ - ATPase , activities in diabetic rat myoctardium .[J];CHINESE JOURNAL OF PATHOPHYSIOLOGY;1997-01
Chinese Journal Full-text Database 10 Hits
1 CHEN Shi-wei,LI Wei-qing(The People′s Hospital of Shenzhen Luohu,Guangdong Shenzhen 518001,China);Effect of Yihua Qingjie Prescription on Inflammatory Molecular Network in Rats with Type 2 Diabetes[J];Journal of Anhui Traditional Chinese Medical College;2008-04
2 WANG Yi-wei1,ZHANG Ju2,CAO Yong-an1,WANG Ping1(1.Department of Biochemistry,Jiangsu Staff Medical University,Nanjing 210029, China; 2.Department of Hand Surgery,China-Japan Union Hospital,Jilin University,Changchun 130033,China);Effects of nerve growth factor on metabolism and function of neuroglial cells of mice[J];Journal of Jilin University(Medicine Edition);2009-03
3 FU Ying1,WANG Yaoguang2,LI Yongchun31.National Olympic Sports Centre,Beijing 100029,China;2.College of Physical Education,Liaoning Normal University,Dalian 116029,China;3.Liaoning Advanced Police Officer School,Dalian 116033,China.;Dynamic Effects of Exercise on Content of IRS-2 and GLUT4 and IRS-2 Tyrosine Phosphorylation in Skeletal Muscle of DM Rats[J];Journal of Capital Institute of Physical Education;2011-04
4 ZHANG Yong-peng1,LIU Jing2,LUO Fei1,ZHU-Feng1,ZHANG Hai-xia1,ZHANG Xiu-qin1,LI Yong-min1(1Hebei North University,Zhangjiakou 075000,China;2Central Blood Bank of Zhangjiakou City,Zhangjiakou 075000,China);Effects of Tangpingjian on serum free fatty acid,leptin,interleukin-6 and tumor necrosis factor-alpha in rats with type 2 diabetes mellitus[J];China Journal of Traditional Chinese Medicine and Pharmacy;2012-02
5 LIU Hong, LUO Lei, GAO Yuan (Department of Physiology, Zhuhai Campus of Zunyi Medical College, Zhuhai 519041, China);Changes of Na~+,K~+-ATPase activity in proximal tubules of type 2 diabetic rats[J];Acta Academiae Medicinae Militaris Tertiae;2006-20
6 HU Bo1, LI Feng1, LI Min1, WANG Sheng-Chun2, LI Jun-Chang1, WANG Han-Min3, ZHANG Ya-Ping41Department of Traditional Chinese Medicine, 2Department of Pharmaceutics, 3Department of Nephrology, 4Department of Endocrinology, Xijing Hospital, Fourth Military Medical University, Xi'an 710033, China;Effect of Zehuang decoction on extracellular matrix expression in rats with diabetic nephropathy[J];Journal of the Fourth Military Medical University;2007-18
7 QIAN Xiao-xian1-3, CHEN Yan-ming4, WU Wei-kang2, 3, LIU Yong1, 2, ZHOU Bin1, 2, LIU Jin-lai1, 2, CHEN Lin1, 2 1Department of Cardiology, 4Department of Endocrinology, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou 510630, China; 2Cardiovascular Institute, 3Institute for Integrated Traditional Chinese and Western Medicine, Sun Yat-sen University, Guangzhou 510080, China;Effects of irbesartan on nitric oxide system in the heart of diabetic rats[J];Journal of Southern Medical University;2006-09
8 CHENG Yi,WEI An-yang,LI Yu-gang Huiqiao Department,Nanfang Hospital,Southern Medical University,Guangzhou 510515,China;Establishment of a rat model of diabetic erectile dysfunction[J];Journal of Southern Medical University;2008-04
9 YUAN Fang, LIU Ying-hong, TIAN Jun-wei, PENG You-ming, LIU Fu-you Department of Nephrology, Second Xiangya Hospital, Central South University, Changsha 410011, China;Renoprotective effect of adiponectin through an antioxidant mechanism in streptozotocininduced diabetic rats[J];Journal of Southern Medical University;2010-03
10 SHI Hong,LIN Ya,YU Wen-zhen (Modern Medicine Department of FCTCM,Fuzhou, Fujian 350003,China);Experimental Study of Dendrobium Compound (DC) on Relieving the Insulin Resistance(IR) in Model Rats[J];Journal of Fujian College of Traditional Chinese Medicine;2004-06
China Proceedings of conference Full-text Database 2 Hits
1 Liu Ji-cheng (Qiqihaer Medical College,Qiqihaer 161042,China);The Affect of Aqueous Extract from Stigma Maydis on the Expression of TGF-β1 and FN in Renal Lesion of Type 2 Diabetic Rats[A];[C];2010
2 ;The Study on Developing a Rat Model with Similarity to the Late Lesion of Type 2 Diabetic Nephropathy[A];[C];2013
Chinese Journal Full-text Database 10 Hits
1 XI Shu-gang1,2,ZHANG Xue-xin2,ZHANG Wen-jie2,WEI Zheng-ren3,ZHAO Chun-yan2 (1.Department of Endocrinology,First Hospital,Jilin University,Changchun 130021,China;2.Department of Physiology,School of Basic Medical Sciences,Jilin University,Changchun 130021,China;3.Department of Pharmacology,School of Basic Medical Sciences,Jilin University,Changchun 130021,China);Protective effect of total arasolides of aralia elata(Miq) seem on cardiomyopathy in rats with early stage diabetes and its mechanism[J];Journal of Jilin University(Medicine Edition);2008-02
2 Han Xueshan, Yang Xufang, Bao Haihua (Mudanjiang Medical College 157011);The Pretective Function of Huanglian Detoxification Decoction onMyocardium Injury of Rats Induced By Streptozotocin[J];Quarterly of Forest By-product and Speciality In China;2004-02
3 WANG Mian, SU Sheng-ou, ZHANG Li-hui,et al. Department of Endocrinology, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, China;The Effects of Rosiglitazone on Cardiomyocyte Apoptosis and Expression of Bax and Bcl-2 in Type 2 Diabetic Rats[J];Journal of Chinese Physician;2005-02
4 ZHANG Ping 1, LIANG Zi wen 1, WANG Hai hui 1, CAI Hong wei 1, ZHANG Su hua 2, WANG Shu ping 2 ( 1Department of Endocrinology, Southwest Hospital, Third Military Medical University, Chongqing, 400038; 2Department of Endocrinology, First Affiliated Hospital, Chongqing University of Medical Sciences, Chongqing 400036, China);Effects of sodium vanadate on GLUT4 translocation in cardiac tissue of streptozotocin-induced diabetic rats[J];Acta Academiae Medicinae Militaris Tertiae;2004-12
5 WU Qi-nan,XIAO Qian,WU Ping,LI Long-ying,GAO Yuan (Department of Gerontology,First Affiliated Hospital of Chongqing Medical University,Chongqing 400016,China);Effect of trimetazidine against the apoptosis of type 2 diabetic rat cardiomyocytes[J];Acta Academiae Medicinae Militaris Tertiae;2007-19
6 WU Jian-she1,GUO Yu-ming2,YANG Han-chun2 , ZHOU YU-Ping2(1.Institute of Animal Husbandry and Veterinary Sciences,Beijing Academy of Agricultre and Forestory Sciences,Beijing 100089,China;2.China Agricultural University,Beijing 100094,China );STUDIES ON THE REGULATIVE EFFECTS OF TRACE ELEMENT COPPER ON IMMUNE FUNCTIONS IN BROILER CHICKS[J];Acta Zoonutrimenta Sinica;2002-01
7 WU Jian-she(Institute of Animal Husbandry and Veterinary Sciences,Beijing Academy of Agriculture and Forestory Sciences,Beijing 100081,China)GUO Yu-ming, ZHOU Yu-ping(College of Animal Sciences and Technology,China Agricultural University,Beijing 10009;STUDIES ON EFFECTS OF DIETARY IRON ON PERFORMANCE AND IMMUNE FUNCTION IN BROILER CHICK[J];ACTA ZOONUTRIMENTA SINICA;1999-03
8 CHEN Gang, LIN Li-xiang, ZHUANG Wei-te, YAO Jin, HUANG Hui-bin, LIANG Ji-xing, ZHANG Fan-lin, WEN Jun-ping, LI Lian-tao, LIN Miao, LIN Qing-min Department of Endocrinology, Fujian Provincial Hospital, Fuzhou 350001, China;Effects of captopril on myocardial tissue energy metabolism and inflammation in rats with diabetic cardiomyopathy[J];Journal of First Military Medical University;2004-07
9 WEI Bo-ping~(1,2),LI Yan~2,DU Gang~2,et al(1.West China School of Pharmacy,Sichuan University,Sichuan Chengdu 610041,China;2.Sichuan Provincial Institute for Food and Drug Control,Sichuan Chengdu 610036,China);Determination of Fe,Zn,Mn,Cu,Se,Cr and Mo in multi-trace elements injection[J];Journal of Pediatric Pharmacy;2006-05
10 Ma Wenqiang, Feng Jie;Effects of iron glycine chelate on oxidative enzymes and parameters in serum of weaned piglets[J];Feed Industry;2008-22
【Secondary Citations】
Chinese Journal Full-text Database 8 Hits
1 Shi Jianhua, et al. (Department of Medicine, Affiliated Hospital of Bcngbu Medical College, Anhui);CLINICAL SIGNIFICANCE OF LEVELS OF SERUM Mg Gr Mn AND Sr IN DIABETICS AND DIABETICS WITH CORONARY HEART DISEASE[J];Journal of Bengbu Medical College;1989-04
2 Sun Jiaxian et al (Department of Endocrinology, The Second Affiliated Hospital);Diabetes with Trace Elements Cr, Cu, Zn and Mg[J];Journal of Harbin Medical University;1989-04
3 Zhan Zhiwei,et al Department of Chinse PLA No 262 Hospital;Relationship Between 8 Elements in Serum of Diabetics and Chronic Complications[J];Tianjin Medical Journal;1989-10
4 XIE Ming-Zhi, LIU Hai-Fan, ZHANG Ling-Yun, SHEN Zhu-Fang and CHEN Qi-Ming(Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing);AN EXPERIMENTAL RAT MODEL OF OBESITY AND DIABETES[J];Acta Pharmaceutica Sinica;1985-11
5 Li Cai, Li Yun-Yi, et al Institute of Preclinical Sciences and Basic Medical College, Norman Bethune University of Medical Sciences, Changchun;Alteration of sarcolemmal integrity of myocardial cells in experimental diabetic rats[J];Chinese Journal of Pathophysiology;1992-01
6 Zhong Ling,Ye Qiu-Rong Department of Pharmacology,College of Medicine,Jinan University, Guangzhou(510632);Protective effects of Acanthopanecis Senticasi on experimental ischemic myocardium[J];CHINESE JOURNAL OF PATHOPHYSIOLOGY;1995-04
7 Liu Rui-Zhi,Li Yan,Zhao Dan,Liu Zi-Hong,Wang Wei-Dong,Zhao Xue-Jian, Lu Wen-Wei,Chen Yu,Zhang Jian,Guo Xin-Wen Lab.of Pathophysiology,Norman Bethune Univ.of Med.Sci.Changchun,(130021)Zhou Zheng-Zhi,Liu Zhong-Rong Chengdu Diao Drug Product Company of Chin;Effects of DAXXK on Na ̄+,K ̄+-ATPase activity and LPO(lipid peroxides)content of myocardial cell membranes in myocardial reperfusion injury dogs[J];CHINESE JOURNAL OF PATHOPHYSIOLOGY;1995-04
8 Xie Zong-chang Qian Zhen-kun Liu Zhong-wei Institute of Integrated TCM and WM, Tongji Medical University, Wuhan (430030);Effect of Ginseng on Antiperoxidate Injury in Myocardium and Erythrocytes of Streptozocin-induced Diabetic Rats[J];Chinese Journal of Integrated Traditional and Western Medicine;1993-05
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