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《Journal of Liaoning Medical University》 2010-01
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The Treatment Effect and Mechanism Research of Carnitine-orotate on Gastric Acid Left

HE Jianru1,WANG Lijun2,SU Yuhong1(1.Liaoning Medical University,Jinzhou 121001 China;2.Chongqing Police Station,Chongqing 400020 China)  
Objective To observe the therapeutic effect of Carnitine-orotate on gastric ulcer and discuss the relevant mechanism.Methods HE dyeing observation was applied into the rat gastric healing process.Elisa test IL-8,IL-10 expression.Immunohistochemical method was applied to test the expression of EGF.Results ①Carnitine-orotate can heal gastric ulcer.②Carnitine-orotate can reduce MDA content of the organization,Strengthen SOD,Through anti-oxidation stress treatment ulcers.③Carnitine-orotate inhibit inflammatory factor IL-8,10 expression and play a role in anti-oxidation.④Carnitine-orotate resistance and promote EGF.Conclusions Carnitine-orotate is effective to treat stomach ulcers mainly through anti-oxidation stresses and promote the expression of EGF.
【Fund】: 辽宁省教育厅重点实验室项目 编号:2009506
【CateGory Index】: R965
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【Citations】
Chinese Journal Full-text Database 2 Hits
1 LU Guo-ming, LI Yu-mei, ZHANG Ming, WANG Qi-zhi(Medical College, Jiaxing College, Jiaxing 314001, China;Department of Gastroenterology, Zhejiang Crops Hospital, Chinese People' s Armed Police Forces , Jiaxing 314000, China; School of Medical, Zhejiang University, Hangzhou 310031, China);Effects of L-arginine on gastric mucosal lesion and acid secretion function of parietal cells in rats under stress[J];Chinese Pharmaceutical Journal;2005-23
2 A Xiang-ren, ZHANG Xin-sheng, LIU Li-ping (Qinghai People′s Hospital, Xining, Qinghai 810007, P.R.China);Change of free radicals in levels of machinese in patients with peptic ulcer at medium altitude*[J];China Journal of Modern Medicine;2006-05
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 LIU A-li,TONG Wu-jun,HE Li-li,GOU Juan(Dept.of Medical Affairs,Lintong Sanatorium of Lanzhou Military Area of PLA,Xi' an 710600,China);Curative Effect and Influence of Salviae Miltiorrhizon Free Radicals of Acute Pancreatitis[J];Medical Journal of National Defending Forces in North China;2007-03
2 WANG Qian,RONG Rong,ZHU Jun-dong,MI Man-tian(Department of Nutrition and Food Hygiene / Chongqing Key Laboratory of Nutrition and Food Safety,College of Preventive Medicine,The Third Military Medical University,Chongqing 400038,China);Hypobaric hypoxia affects digestion and absorption of carbohydrates in rats[J];Journal of Medical Postgraduates;2009-10
3 Xie Xiaoli Wang Minqi;Regulatory function of arginine on animal intestine mucosal immunity[J];China Feed;2008-04
4 Qu Chunying,Li Dingguo,Wang Yuqin,Chen Meimei(Xinhua Hospital of Medical Instite of Shanghai Jiaotong University,Shanghai,200092);Effect of chitosan on the serum levels of MDA,SOD,and GSH-Px in rats with gastric ulcer[J];Shanghai Medical & Pharmaceutical Journal;2008-05
5 MENG Fan-dong,ZHANG Shu-tian,ZHOU Qiao-zhi,YU Zhong-lin.The Department of Gastroenterology,Beijing Friendship Hospital Capital Medical University,Beijing 100050,China;A systematic review of eradicating helicobacter pylori with ranitidine bismuth citrate[J];Chinese Journal of Practical Internal Medicine;2009-02
6 YU Liang-zhu,HUANG Bi-lan,WANG Bang-hua,DING Jie-qiong,TANG Qiong (Department of Physiology,Medical School of Xianning College,Xianning Hubei,437100 China);Effects of Ginkgo biloba Extract on Pylorus Ligated Gastric Ulcer in Rats[J];Lishizhen Medicine and Materia Medica Research;2007-07
7 DU Xu, WANG Jin-hua,LIU Pu (The First Hospital Affiliated with Harbin Medical University, Harbin150001);EFFECTS OF WENQINGYIN ON SERUM MDA AND SOD OF RATS WITH STRESS ULCER OF STOMACH[J];Chinese Journal of Traditional Medical Science and Technology;2009-03
8 ZHANG Xiaohong, YANG Zheng, XU Yan, ZHANG Xiao. Class 5, Grade 2006, Clinical Undergraduate Course, Chengdu Medical College, Chengdu (610083)Department of Experimental Technology,Chendu Medical University;Effects of Endogenous Factors on Gastric Ulcer[J];Chinese Journal of Gastroenterology;2008-06
9 Deng Yan, Chen Wei-hua, Song Xiao-dan, Zhang Yuan-shuCollege of Veterinary Medicine, Nanjing Agricultural University, Key Open Laboratory of Physiology and Biochemistry of Ministry of Agriculture, Nanjing 210095, Jiangsu Province, China;Effect of different frequencies of vibration on gastric mucus secretion and mucosal structure in rats[J];Journal of Clinical Rehabilitative Tissue Engineering Research;2008-09
10 Cheng-Guo Wang Qing-Jiu Ma Jian-Guo Lu Xian-Li He Qing Wang Xi-Lin Du Yan-Kui Chu Department of General Surgery,Tangdu Hospital,the Fourth Military Medical University,Xi'an 710038,Shaanxi Province,China;Therapeutic effect of kadsurenone on acute pancreatitis in rats[J];World Chinese Journal of Digestology;2007-04
【Secondary Citations】
Chinese Journal Full-text Database 6 Hits
1 ;消化性溃疡患者血中LPO含量、SOD及GSH-PX活性观察[J];World Chinese Journal of Digestology;2000-04
2 WU Nan, WANG Shou-jiu, WANG Sheng-gen, PAN Gui-hong (Department of gastroenterology, the 414th hospital of PLA, Nanjing JIANGSU 210015, China);Comparison of three kinds of short-term triple therapies for eradication of Helicobacter pylori infection[J];Chinese Journal of New Drugs and Clinical Remedies;2002-11
3 LI Yu-mei 1,2 , ZOU Xiao-ping 1, LI Zhao-shen 1, PENG Gui-yong 3, ZHAN Xian-bao 1, TU Zhen-xing 1, FANG Dian-chun 3, XU Guo-ming 1 ( 1 Department of Gastroenterology, Changhai Hospital, the Second Military University, Shanghai 200433, China; 2 Zhejiang Crops Hospital, Chinese People's Armed Police Forces, Jiaxing 314000, China; 3 Xi'nan Hospital, The Third Military University, Chongqing 400038, China);Dynamic changes of the function and ultrastructure of gastric parietal cells under stress ulcer in rats[J];Chinese Journal of Pathophysiology;2003-08
4 ZHANG Zhi yu 1, ZHAI Cheng 1, QIAN Cong 1, MA Xue wen 2 (1.School of Pulblic Health, China Medical University, Shenyang 110001, China; 2.Benxi 65559 Hospital for Liberation Army, Benxi 117022, China);Effect of non-enzyme reaction on measuremeut of glutathione peroxidx activity in blood and its exclusion[J];Chinese Jouranl of Endemiology;2001-06
5 Zhao Yunbin, Liu Min, Yu Zhongyi. Department of Chemistry, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China;Determination of Superoxide Dismutase Activity in Blood by method of Pyrograllol Autoxidation[J];Chinses Journal of Health Laboratory Technology;2001-04
6 DAI Xing-ping1, XU Mei-hua2, JIANG Rong-xin1, ZHOU Yong-jie1, LI Xia-ling1, LI Jia-bang1(1.Institute of Integrated Traditional Chinese and West Medicine, Central South University Xiangya Hospital, Changsha, Hunan 410008, P.R China; 2.Department of Gastroenterology, Central South University Xiangya Hospital, Changsha, Hunan 410008, P.R China);Effect of Jianweiyuyang Granules on expression of VEGF mRNA of human peptic ulcer margin*[J];China Journal of Modern Medicine;2004-20
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