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Clinical Observation of Omeprazole Jiont Clarithromycin in the Treatment of 48 Case Chronic Gastritis

YE Jianfei(Medical Department,Affiliated Hospital of Fuzhou University,Fuzhou 350001 China)  
Objective To investigate the clinical effect of omeprazole jiont clarithromycin in the treatment of chronic gastritis.Methods 88 patients with chronic gastritis in our hospital were randomly divided into two groups,40 cases in Group A treated by omeprazole and 48 cases in Group B treated by omeprazole plus clarithromycin,and then the effects were observed after 4 weeks' continuous treatment.Results For total therapy efficiency rate,Group A and Group B proved to 80.00% and 95.83% respectively,the therapeutic effect of Group B is better than that of Group A(P0.05),for eradication rate of H.pylori,Group A and Group B were 55.00% and 87.50% respectively,H.pylori eradication rate of Group B is higher than Group A(P0.05),for incidence of adverse reaction such as nausea and dizziness,Group A and Group B were 12.50% and 14.58% respectively,the incidence of adverse reactions in two groups was not significantly different(P0.05).Conclusion Combining Omeprazole with clarithromycin into the treatment of chronic gastritis can achieve more significant effect will bring about fewer adverse reactions and higher H.pylori eradication rate,which makes it worthy to be popularized in clinical application.
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