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《Journal of Liaoning Medical University》 2013-01
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Exploration of the Detection and Clinical Significance of hs-CRP in COPD Patients

WANG Yanbing(The Fifth People's Hospital of Nanhai District,Foshan,Foshan 528231 China)  
Objective To investigate the changes of the level of serum hs-CRP in COPD patients with acute exacerbation and to explore its relevant clinical significance.Methods A total of 68 COPD cases with acute exacerbation were collected in our hospital from June 2010 to June 2011.All patients were divided into ClassⅠ,Ⅱ,Ⅲ and Ⅳ according to the severity of pulmonary dysfunction.Another 30 healthy subjects from health-care centre were used as the normal control.The level of serum hs-CRP was measured with Latex enhanced immunoturbidimetric assay.Results The expression of serum hs-CRP was(16.42±5.43 and 9.61±2.33)μg/mL before and after treatment,which was significantly higher than that in control group(5.58±1.24)μg/mL(P0.01).There was significant increase of hs-CRP before and after treatment(P0.01).The expression of hs-CRP in Ⅰ,Ⅱ,Ⅲ,and Ⅳ pulmonary dysfunction classes was(8.14±2.52),(10.16±3.31),(17.55±4.81)and(22.84±5.72)μg/mL,respectively.There was significant statistical difference among different groups(P0.05).Conclusion The expression of hs-CRP increased in COPD patients with acute exacerbation,which could be used to monitor COPD patients with acute exacerbation.
【CateGory Index】: R563.9
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