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《Journal of Liaoning Medical University》 2013-01
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Clinical Observation of Compound Matrine Injection Combined with SP Regimen in Advanced Gastric Cancer

XIA Guo'an(Department of Oncology,Chizhou Second People's Hospital of Anhui Province,Chizhou 247100 China)  
Objective To investigate the clinical effect of compound matrine injection combined with SP in the treatment of advanced gastric cancer effect.Methods 76 cases with advanced gastric cancer were collected in our hospital from June 2010 to November 2011 and randomly divided into experimental group and control group.Patients in the two groups were treated with compound matrine injection combined with SP regimen and SP regimen respectively;clinical effect of the two groups was compared.Results The effective rate of experimental group and control group was 57.5% and 52.8% respectively.Therapeutic effect of the two groups of patients did not differ significantly.Except that there was no significant difference in terms of nausea and vomiting symptoms,occurrence rate of other indexes of the treatment group were lower than those of control group.Conclusion The treatment of advanced gastric cancer with compound matrine injection combined with SP program can significantly reduce the abnormal rate of white blood cells,the abnormal rate of hemoglobin,the abnormal rate of liver function,the incidence of diarrhea and constipation and the incidence of neurotoxicity,so as to improve the life quality of patients with advanced gastric cancer.
【CateGory Index】: R735.2
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【References】
Chinese Journal Full-text Database 1 Hits
1 XU Jinxiu,ZHAO Shiye,WANG Airong,WANG Wenjing(The Tumor Hospital of Weihai Municipal Hospital,Weihai 264200,Shandong,China);Clinical Observation of Compound Kushen Injection Combined With FOLFOX Regimen in Treatment of Advanced Gastric Cancer[J];Chinese Archives of Traditional Chinese Medicine;2013-08
【Citations】
Chinese Journal Full-text Database 2 Hits
1 LI Rui-ping,HU Xue-mei,L Yin-feng,WANG Mei,GUO Yu-zhen(Department of Obstetrics and Gynecology,the Second AffiliatedClinical Hospital of Lanzhou University,Lanzhou 730030,China);Effects of matrine on proliferation of human ovarian cancer cells and the action mechanism[J];Journal of Xi'an Jiaotong University(Medical Sciences);2010-05
2 SUN Xiu-di *, MU Ren, ZHOU You-shang, DAI Xu-dong, ZHANG Si-wei, HUANGFU Xi ao-mei, SUN Jie, LI Lian-di, LU Feng-zhu,QIAO You-lin. *Cancer Institute (Hospital), Chin ese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, C hina;Analysis of mortality rate of stomach cancer and its trend in twenty years in China[J];Chinese Journal of Oncology;2004-01
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 WANG Xiang-ming1,YU Dong-hong2,WANG Ping2,ZHANG Fan1,CAI Zhao-gen2,ZHOU Lei2,CHENG Ze-nong2(1.Department of Pathology,Yijishan Hospital,Wannan Medical College,Wuhu 241001,Anhui;2.Department of Pathology,Bengbu Medical College,Bengbu 233030,Anhui,China);Inhibitory Effects of Sulindac on Xenograf Growth and Angiogenesis in Gastric Cancer[J];Carcinogenesis,Teratogenesis & Mutagenesis;2008-05
2 Department of Oncology The People's Hospital of Lu'an,Lu'an 237005. Anhui WANG Ping;Vinorelbine plus Cisplatin Chemotheapy in the Treatment of Advanced Non-small cell Lung Cancer[J];Journal of Anhui Health Vocational & Technical College;2007-06
3 YANG Xue-yingOncology Department of Chizhou Second People's Hospital,Chizhou 247000,Anhui;Observation and nursing of patients undergoing chemotherapy[J];Journal of Anhui Health Vocational & Technical College;2008-03
4 ZHAN Sheng-wei,BIAN Zheng-ping,CAI Hua-ying (Maanshan Center for Disease Control and Prevention,Maanshan,Anhui,243011,China);The Analysis of Trends on Mortality of Male Residents Lung and Stomach Cancer in Maanshan City from 1983 to 2004[J];Anhui Journal of Preventive Medicine;2007-02
5 LIN Feng,TANG Xiao-chun,CAI Xun,YAO Yang (Department of Oncology,Shanghai Jiaotong University Affiliated Sixth People's Hospital,Shanghai 200233,China);Clinical study on the new adjuvant chemotherapy for the treatment of osteosarcoma[J];Anhui Medical and Pharmaceutical Journal;2005-05
6 CHI Yu,YU Qing-chen,CHENG Dao-ju,CAO Ji-yu(The Second Hospital of Laian County,Chuzhou Anhui 239236);A case-control study on the relationship between dietary factors and gastric cancer[J];Anhui Medical and Pharmaceutical Journal;2009-04
7 WANG Yue-hua,LIU Zhi,LI Liang-liang(Department of Oncology,Tongling People's Hospital,Tongling,Anhui 244000);Clinical observation of FOLFOX4 regimen for advanced gastric cancer[J];Anhui Medical and Pharmaceutical Journal;2011-08
8 ZHANG Zhang,LIU Peng-ying,QIN Ling,et al(Wuhu No.2 People's Hospital,Wuhu,Anhui 241000);Gemcitabine and cisplatin combination chemotherapy of artery and vein in advanced pancreatic cancer[J];Anhui Medical and Pharmaceutical Journal;2012-02
9 XIE Cong Ying, WU Shi Xiu, ZHANG Ping Department of Oncology, The First Affiliated Hospital of Wenzhou Medical College, Wenzhou,Zhejiang,325000, P.R.China;Efficacy of Combined Paclitaxel and Oxaliplatin Therapy in Patients with Pretreated Advanced Non Small Cell Lung Cancer[J];Chinese Journal of Cancer;2004-08
10 ZHANG Xue Mei1, 2△, MIAO Xiao Ping2△, XIONG Ping2, YU Chun Yuan2, TAN Wen2, QU Shi Ning2, SUN Tong2, ZHOU Yi Feng2, LIN Dong Xin21.Department of Biological Sciences,North China Coal Medical College,Tangshan,Hebei,063000,P.R.China2.Department of Etiology &Carcinogenesis,Cancer Institute,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing,100021,P.R.China;Association of Functional Polymorphisms in Matrix Metalloproteinase-2 (MMP-2) and MMP-9 Genes with Risk of Gastric Cancer in A Chinese Population[J];Chinese Journal of Cancer;2004-11
China Proceedings of conference Full-text Database 3 Hits
1 Zhang Jingshu1 Wang Chunhua1 Chen Bingqing2 Yang Yanmei2 Gao Yanhui2 Sun Wenguang2 (1.Department of Toxicology, Tianjin Centers For Disease Control And Prevention , Tianjin 300011, China;2.Department of Nutrition and Food Hygiene, Public Health College, Harbin Medical University, Harbin, 150086 , China);Study on inhibitory effects of c9,t11-conjugated linoleic acid on matrix metalloproteinase of human gastric carcinoma cell line(SGC-7901) via cyclooxygenase-2 pathway[A];[C];2008
2 ZHAO Shu,ZHANG Qingyuan,SUN Wenzhou,ZHAO Rui,LI Hongbin.Medical WardⅢ,The Tumour Hospital of Harbin Medical Univerdity,Harbin 150081,China;Gemcitabine combined cisplatin and methylprednisolone in the treatment of relapsed or refractory T-cell non-Hodgkin's lymphoma[A];[C];2009
3 ;局部晚期胃癌序贯放化疗与单纯化疗的临床随机观察[A];[C];2009
【Co-references】
Chinese Journal Full-text Database 9 Hits
1 Jian-Guo Zhao,1,2 Jian-Ping Xiong,2 Xiao-Jun Xiang,2 Feng Qie,2 Ling Zhang2 and Feng Yu21. Department of Oncology, Shaoxing People's Hospital, Shaoxing, Zhejiang, 312000, P. R. China 2. Department of Oncology, The First Affiliated Hospital, Nanchang University, Nanchang, Jiangxi, 330006, P. R. China;A phase Ⅱ trial of epirubicin plus oxaliplatin and fluorouracil as first-line chemotherapy for advanced gastric cancer[J];Chinese Journal of Cancer;2009-01
2 ;Kushen Compound Injection Combined with FOLFOX4 Regimen in the Treatment of Gastrointestinal Tumor[J];Hubei Journal of Traditional Chinese Medicine;2013-02
3 ZENG Hui , HU Mei-jie , ZHANG Shu , QIAO Mim-min , ZHANG Yong-ping, SHI Gui-ying, WU Yun-lin (Department of Gastroenterology, Ruijin Hospital, Shanghai Second Medical University, Shanghai 200025 , China; Deparment of Cell Biology, College of Basic Medicine,Shanghai Second Medical University);Cytotoxicity effect of matrine on gastric cancer cell lines in vitro[J];Acta Universitatis Medicinalis Secondae Shanghai;2004-01
4 XIONG Liang-geng. Department of Oncology,Dazhou No.2 Hospital,Dazhou,635000;Clinical Observation of Yanshu Injection Combined with Paclitaxel and Oxaliplatin in the Treatment of Advanced Gastric Cancer[J];The Practical Journal of Cancer;2008-03
5 ZHANG Ming-jie,HUANG Jian (The Second Affiliative Hospital of Zhejiang University,Hangzhou 310009, China);Recent research progress of anti-tumor mechnism matrine[J];China Journal of Chinese Materia Medica;2004-02
6 TIAN Juan1,2,WANG Wei-hao1,GAO Hui-min1,WANG Zhi-min1(1.Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences,Beijing 100700,China;2.College of Life Science,Northwest Sci-Tech University of Agriculture and Forestry,Yangling 712100,China);Determination of matrine,sophoridine and oxymatrine in compound Kushen injection by HPLC[J];China Journal of Chinese Materia Medica;2007-03
7 ZHENG Rong-shou 1,ZHANG Si-wei 1,WU Liang-you 2,et al.(1.National Cancer Center,Beijing 100021,China;2.Disease Prevention and Control Bureau,Ministry of Health,Beijing 100044,China);Report of Incidence and Mortality from China Cancer Registries in 2008[J];China Cancer;2012-01
8 WANG You-chun,MA Jian-dang.Department of Gastroenterology.the central Hospital of Luoyang,Henan 471009,China;Clinical Observation of Yan-shu Injection Combined with 5-Fu and DDP in the Treatment of Gastric Cancer[J];China Practical Medicine;2009-17
9 BAO Wen-long,FANG Mei-yu,JIANG Chu-ming,DENG Den-hou,GU Dan-lin(Zhejiang Cancer Hospital,Hangzhou 310022,Zhejiang,China);Clinical Observation on Efficacy of Fuzheng Kang'ai Decoction Combined with Chemotherapy on Advanced Gastric Cancer[J];Chinese Archives of Traditional Chinese Medicine;2012-11
【Secondary Citations】
Chinese Journal Full-text Database 3 Hits
1 Zhou J, Luo RB, Tang CF, Qu SL. 1Department of Human Science and Kinesiology, Institute of Physical Education, Hunan Normal University, Changsha 410012, Hunan Province, China; 2Xiangnan College, Chenzhou 423000, Hunan Province, China;Effect of Bcl-2 protein family and p53 gene on regulating and controlling cell apoptosis[J];Journal of Clinical Rehabilitative Tissue Engineering Research;2007-10
2 JIANG Hao,FAN Guang hua (Clinical Oncology Research Center,the First Affiliated Hospital of Nanhua University,Hengyang 421001,China);Efficacy of ginsenoside-Rh_2 on proliferation and apoptosis for Bel-7404 cell line[J];Chinese Journal of Clinical Oncology and Rehabilitation;2004-04
3 SUN Xiudi *, MU Ren, ZHOU Youshang, DAI Xudong, QIAO Youlin, ZHANG Siwei, HUANGFU Xiaomei, SUN Jie, LI Liandi, LU Fengzhu. *Cancer Institute (Hospital), Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China;1990-1992 mortality of stomach cancer in China[J];Chinese Journal of Oncology;2002-01
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