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Clinical Observation of Compound Matrine Injection Combined with SP Regimen in Advanced Gastric Cancer

XIA Guo'an(Department of Oncology,Chizhou Second People's Hospital of Anhui Province,Chizhou 247100 China)  
Objective To investigate the clinical effect of compound matrine injection combined with SP in the treatment of advanced gastric cancer effect.Methods 76 cases with advanced gastric cancer were collected in our hospital from June 2010 to November 2011 and randomly divided into experimental group and control group.Patients in the two groups were treated with compound matrine injection combined with SP regimen and SP regimen respectively;clinical effect of the two groups was compared.Results The effective rate of experimental group and control group was 57.5% and 52.8% respectively.Therapeutic effect of the two groups of patients did not differ significantly.Except that there was no significant difference in terms of nausea and vomiting symptoms,occurrence rate of other indexes of the treatment group were lower than those of control group.Conclusion The treatment of advanced gastric cancer with compound matrine injection combined with SP program can significantly reduce the abnormal rate of white blood cells,the abnormal rate of hemoglobin,the abnormal rate of liver function,the incidence of diarrhea and constipation and the incidence of neurotoxicity,so as to improve the life quality of patients with advanced gastric cancer.
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