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The Growth-promoting Effect of Gastrin on Colorectal Cancer and the Development of Anti-gastrin Treatment

ZHAO Yufeng,WU Pei(Gastrointestinal Surgery,Yijishan Affiliated Hospital of Wannan Medical College,Wuhu 241000 China)  
Gastrin exists widely in gastrointestinal tract and pancreatic tissues,and plays an important role in the adjustment of physiological functions and pathogenic mechanism of some diseases.Recent studies show that gastrin might lead to the development of tumors,especially digestive tumors such as gastric cancer and colorectal cancer.It is promising to apply gastrin clinically to endocrine therapy for gastrin can speed up cell proliferation and inhibit apoptosis.
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