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《Journal of Jinzhou Medical University》 2017-01
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Observation of Curative Effect of Tacrolimus Ointment Combined with Excimer Laser on Patients with Plaque Psoriasis

LIU Wei;ZHANG Guoqing;HE Jinliang;CAO Lijun;Department of Dermatology of TCM,Yangang Hospital of Yantian District,Shenzhen;  
Objective To explore the curative effect of tacrolimus ointment combined with excimer laser on patients with plaque psoriasis. Methods 144 patients with plaque psoriasis were selected and randomly divided into combination group,laser group and drug group. The clinical effect,PASI and DLQI scores before and after treatment,target skin injury,score of itching degree,satisfaction with the curative effect and adverse reactions of the three groups were compared. Results Compared with the drug group and the laser group,the combination group had significantly higher total effective rate,lower PASI and DLQI scores after treatment,less erythema,scale,hypertrophy,and itching,and higher satisfaction with the treatment effect,with statistically significant difference( P 0. 05). There was no statistically significant difference in the incidence of adverse reactions among the three groups( P 0. 05). Conclusion Tacrolimus ointment combined with excimer laser can improve the clinical effect on plaque psoriasis,clinical symptoms of patients,and their satisfaction with treatment effect,with higher safety,worth promoting.
【CateGory Index】: R758.63
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【Citations】
Chinese Journal Full-text Database 2 Hits
1 QUAN He-he;MIU Da-hong;JIN Wan-wan;Department of Dermatolo-gy,Second Affiliated Hospital of Wenzhou Medical University;;Efficacy and safety evaluation of tacrolimus ointment combined with excimer laser treatment for plaque psoriasis[J];实用药物与临床;2015-11
2 LI Wei,WANG Li-xin,LIU Yin,ZHANG Xi-bao(Guangzhou Institute of Dermatology,Guangzhou 510095,China);Clinical Efficacy of 0.03% Topical Tacrolimus Ointment Combined with 308nm Excimer Laser in Treatment of Psoriasis Vulgaris[J];中国皮肤性病学杂志;2012-12
【Co-citations】
Chinese Journal Full-text Database 4 Hits
1 QUAN He-he;MIU Da-hong;JIN Wan-wan;Department of Dermatolo-gy,Second Affiliated Hospital of Wenzhou Medical University;;Efficacy and safety evaluation of tacrolimus ointment combined with excimer laser treatment for plaque psoriasis[J];实用药物与临床;2015-11
2 XIONG Guo-fang;The Second People's Hospital of Boxing County Shandong Province;;Effects of Excimer Laser Irradiation on the Imbalanced Ratio between Th17/Treg and Their Cytokines Expression in Patients with Psoriasis Vulgaris[J];中国皮肤性病学杂志;2015-09
3 SU Li-na;YI Xue-mei;DING Yang-feng;YU Ning;MA Jun;Shanghai Skin Disease Hospital;;Assessment of Clinical Efficacy and Influence on Life Quality of Chinese Medicine Bath Combined with 308nm Excimer Laser in the Treatment of Plaque Psoriasis[J];中国皮肤性病学杂志;2015-09
4 Xiong Guoxin;Li Xinzhong;School of Physics and Engineering,Henan University of Science and Technology;;Effects of Excimer Laser Irradiation on the Expression of the Th17,Treg and Their Cytokines in Patients with Psoriasis Vulgaris[J];应用激光;2015-02
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Chinese Journal Full-text Database 10 Hits
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5 LI Wei,WANG Li-xin,LIU Yin,ZHANG Xi-bao(Guangzhou Institute of Dermatology,Guangzhou 510095,China);Clinical Efficacy of 0.03% Topical Tacrolimus Ointment Combined with 308nm Excimer Laser in Treatment of Psoriasis Vulgaris[J];中国皮肤性病学杂志;2012-12
6 HAO Yong,SHI Ji-hai,HAN Hui,JI Mu-si,ZHANG Xiao-yan,YANG Yue-yuan (Department of Dermatology,the Second Affiliated Hospital of Baotou Medical College, Baotou Inner Mongolia 014030, China);The Effects of Tacrolimus Ointment on Proliferation and Differentiation of Keratinocytes in Psoriatic Lesions[J];中国皮肤性病学杂志;2012-09
7 FU Lan1*,JI Chao2,LI Xian-guang3,TU Ying1,QI Jue1,HE Li1 (1. Department of Dermatology, First Affiliated Hospital of Kunming Medical College, Kunming 650032, China; 2. First Affiliated Hospital of Nanjing Medical University, Nanjing 210024, China; 3. Department of Dermatology,Kunming Yanan Hospital,Kunming 650051,China;* First People’s Hospital of Kunming City, Kunming 650011,China);Clinical Trial of Tacrolimus Ointment for Treatment of Photoallergic Dermatitis in Adults[J];中国皮肤性病学杂志;2012-09
8 JIANG Jing 1,XIA Li-jun2(1.Department of Dermatology,Nankai Hospital,Tianjin 300100,China;2.Tianjin University of Traditional Chinese Medicine,Tianjin 300179,China);Thirty-nine Cases of Hormone-dependent Facial Dermatitis Treated with Tacrolimus Ointment and Recombinant Human Epidermal Growth Factor Gel[J];中国皮肤性病学杂志;2012-06
9 DENG Wei 1 ,GUO Zai-pei 2 (1. Department of Dermatovenereology,Central Hospital of Dazhou City,Dazhou 635000,China; 2. Department of Derma- tovenereology,West China Hospital of Sichuan University,Chengdu 610041,China);Efficacy and Safety of 308-nm Excimer Laser on Vitiligo: A Systematic Review[J];中国皮肤性病学杂志;2012-06
10 LIU Jun-ru1, ZHANG Jun-ling2, CHENG Lin1, XU Shi-fu1, MA Xiu-liang2(1.Graduate school of Tianjin Medical University,Tianjin 300070,China;2 Department of Pigmentation Dermatology, Tianjin Changzheng Hospital, Tianjin 300120,China);Clinical Study of Combination Therapy of 308nm Excimer Laser and Topical Tacrolimus for Treatment of Vitiligo[J];中国皮肤性病学杂志;2012-05
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