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《Primary Journal of Chinese Materia Medica》 1999-02
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The Compatible Stability of Puerarin Injection and Cefazolin Sodium Injection

Lu Mei The People's Hospital of Guangxi Autonomous Region, Nanning 530021  
OBJECTIVE: The compatible stability of puerarin injection with cefazolin sodium in-jection in 0.9% sodium chloride injection was studied. METHOD:A HPLC method was developed by using a NoVa-Pak C[18] column(4 um,3.9×150 mm). A mixture of methanol-water(25:75) was used as the mobile phase with a flow rate of 0. 8 ml per minute and the detection wavelength was set at 254 nm. The contents of two drugs' were calculated by external-standard method. RE-SULTS: The compatibility of the two drugs was feasible and no significant change was found in the appearance,pH and content of the solution at 37 C in 8 hours. CONCLUSON:The mixture of puerarin and cefazolin sodium in 0.9% sodium chloride injection can be used in the clinic therapy.
【CateGory Index】: R283
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