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《Primary Journal of Chinese Materia Medica》 1999-02
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Effect of Hyperin on Calcium ion Content in Nervous Tissue

Cen Deyi, Chen Zhiwa, Xi Jin et al. (Dept. of Pharmacology Anhui Medical University, Hefei230032)  
OBJECTIVE:To study the effect of Hyperin (Hyp. ) on calcium ion content in ver-vous tissue. METHOD: Calcium ion content in the isolated sciatic nerve of frog was measured with atomic absorption spectrophotometer. RESULTS: Hyp.1×10-5,1×10-6,and 1×10-7mol L-1markedly inhibited.the increase of Ca2+content evoked by K+50 mmol. L-1 in a concentration depentent manner. Hyp: 10-4mol ?1L-1 inhibited the increace of Ca+2 content induced by NE 10-5 mol. L-1. CONCLUSION: Hyp. had inhibitory effect on influx of Ca2+ in nervous tissue.
【CateGory Index】: R285.5
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