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Therapy Action of Shenda Granule on Chronic Renal Functional Failure Modelby Resection Five Sixths Kidney in Rats

Long Zi jiang,Wei Jianglei,Lu Xiaoyin (Anhui College of T.C.M.,Hefei 230038)  
OBJECTIVE:To observe the therapy action of Shenda granule on chronic renal functional failure model by resection five sixths kidney in rats.METHODS:Rats that kidney were resected five sixths under anesthetization by ether are made animal model of chronic renal functional failure.After 5 weeks,Shenda granule were used in ig.at dosage of 5.0,12.5g/kg,and continued 4 weeks.To take urina volume and determine BUN,Cr,TP in urina and RBC,Hb in blood and observe the change of renal tissue.RESULTS:After taking the medicine,urina volume,BUN,Cr,TP in urina,and BUN,Cr in plasma are all decline,and TP in plasma,RBC,Hb are rise,and to improve the renal tissue pathologic change.CONCLUSION:Shenda granule can obviously cure the animal model of chronic renal functional failure.
【CateGory Index】: R285
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