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《Research and Practice on Chinese Medicines》 2007-01
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Determination of Ferulic Acid in Zhongfenghuichun Capsules by HPLC

LEI Ya-xian,WANG Qiao-ling,GAO Xiang-xiang,YAO Wei(Xianyang Buchang Pharmaceutical Co.,Ltd,Xianyang 712000,China)  
Objective A HPLC method was established for the determination of ferulic acid in Zhongfenghuichun capsules.Methods Kromasil C18 column(4.6 mm×200 mm,5 μm) was used,the mobile phase consisted of acetonitrile-(0.1%)phosphoric acid solution(20:80),the flow rate was 1mL·min-1,the detection wave length at 325nm.Results The calibration curve was in good linearity over the range of 0.05~0.25 μg with the regression equation of Y=26113X-8154.8,r=0.999 6.The average recovery was 97.98% with RSD of 0.74%.Conclusion The method was simple,accurate,reproducible,and could be used for the control of the quality of Zhongfenghuichun capsules.
【CateGory Index】: R286
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