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《Chinese Science Bulletin》 2014-02
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Research progress and applications of self-assembled DNA nanostructures

GE ZhiLei;FAN ChunHai;YAN Hao;Laboratory of Physical Biology,Shanghai Institute of Applied Physics,Chinese Academy of Sciences;Center for Single Molecule Biophysics,The Biodesign Institute,Arizona State University;  
DNA nanotechnology is an example of bottom-up molecular self-assembly,in which molecular components spontaneously organize into stable structures;the particular form of these structures is induced by the physical and chemical properties of the components selected by the designers.In this field,nucleic acids are used as non-biological engineering materials for nanotechnology rather than as the carriers of genetic information in living cells.This use is enabled by the strict base pairing rules of nucleic acids,which cause only portions of strands with complementary base sequences to bind together to form strong,rigid double helix structures.This allows for the rational design of base sequences that will selectively assemble to form complex target structures with precisely controlled nanoscale features.This article mainly reviews the developments of DNA self-assembly achieved recently and also introduces the design methods of it,which would be helpful and enlightened for our future research.
【CateGory Index】: TB383.1
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Chinese Journal Full-text Database 4 Hits
1 WEI Min;LI Jiang;CHEN Nan;HUANG Qing;FAN ChunHai;Laboratory of Physical Biology,Shanghai Institute of Applied Physics,Chinese Academy of Sciences;;CpG ODN delivery systems based on nanomaterials[J];Chinese Science Bulletin;2014-02
2 FU Yanming1,2,PEI Hao1,ZENG Dongdong1,HUANG Qing1,FAN Chunhai1 1.Laboratory of Physical Biology,Shanghai Institute of Applied Physics,Chinese Academy of Sciences,Shanghai 201800,China;2.Northeast Forestry University,Harbin 150040,China;An Scaffolded DNA Origami Algorithm for Polygon Network Structures and Hollow Three-Dimensional Structures[J];Acta Biophysica Sinica;2010-08
3 FU Yan-Ming a,c,ZHANG Zhao b,LI Can b,SHI Yong-Yong b,YAN Xiu-Feng a,FAN Chun-Hai c(aNortheast Forestry University,Harbin;bBio-X Center,Shanghai Jiao Tong University,Shanghai;cShanghai Institute of Applied Physics,Chinese Academy of Sciences,Shanghai 201800);Recent Progress in DNA Origami[J];Chinese Journal of Applied Chemistry;2010-02
4 HUANG Chun;HOU He-wei;YE Meng-meng;LI Meng-meng;CUI Guang-zhao;WANG Yan-feng;College of Electric Information Engineering,Zhengzhou University of Light Industry;;Research status and application of structural DNA nanotechnology[J];Journal of Zhengzhou University of Light Industry(Natural Science Edition);2014-01
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