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《Chinese Science Bulletin》 2014-02
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Real-time functional magnetic resonance imaging and its applications

L BingJiang;ZHAO XiaoJie;YAO Li;GAO JiaHong;Beijing City Key Laboratory for Medical Physics and Engineering,Peking University;Center for Magnetic Resonance Imaging (MRI) Research,Academy for Advanced Interdisciplinary Studies,Peking University;College of Information Science and Technology,Beijing Normal University;State Key Laboratory of Cognitive Neuroscience and Learning,Beijing Normal University;IDG/McGovern Institute for Brain Research,Peking University;  
Real-time functional magnetic resonance imaging(rtfMRI) has made it possible to gain accesses to brain cortex activities immediately in an on-going experiment by analyzing data as fast as they are acquired.The continuously updated hemodynamic results could be used as neruo-feedback to build a closed information loop.Recently improvements in acquisition techniques and processing algorithms along with advances in computational power have facilitated the development of rtfMRI and its applications in neuroscience and clinical therapy.Preliminary evidence suggested that self-regulation of certain brain areas could be achieved by rtfMRI neuro-feedback,resulting in the changes of related cognitive processes or behaviors,which provides a novel paradigm for cognitive neuroscience.rtfMRI can also be used as a brain-computer interface with high spatial resolution and whole brain coverage.Since brain states can be decoded and classified in real time,interactions with the outside could be dependent only on brain activities.In addition,the potential usage of rtfMRI for clinical applications has drawn public attentions.Patients might be able to modulate their abnormal brain activation using neuro-feedback based on rtfMRI,thus it has been suggested as a new tool for the treatment and rehabilitation of neurological or pathological disorders.This article aims to review the core concepts,key techniques and related applications of rtfMRI.Current problems and future directions are also discussed at the end.
【Fund】: 国家自然科学基金(81227003 60931003 61071178);; 国家科技支撑计划(2011BAI12B01)资助
【CateGory Index】: R445.2
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【Co-citations】
Chinese Journal Full-text Database 5 Hits
1 MA Lijia;SHI Dapeng;GUAN Min;Department of Radiology,People’s Hospital of Henan Province ,Affiliated of Zhengzhou University;;The research progress of real-time fMRI neurofeedback[J];International Journal of Medical Radiology;2014-03
2 Zhang Yushun1,2,Fan Fenling2,Tian Hongyan2,Feng Jun2,Ma Xiancang3,Liu Yamin2,Hu Zhi2,Zhang Junbo2,Ma Yexin11Department of Cardiology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China 2Department of Cardiovascular Medicine,First Affiliated Hospital,Medical College,Xi'an Jiaotong University,Xi'an 710061,China 3Department of Psychology and Psychiatry,First Affiliated Hospital,Medical College,Xi'an Jiaotong University,Xi'an 710061,China;Role of ghrelin in cognitive impairment of hypertensive elders with chronic psychological distress[J];中国人民解放军军医大学学报(英文版);2010-03
3 Fen-Ling Fan1,Yu-Liang Zou2,Ai-Qun Ma1,Hong-Yan Tian1,Jun-Bo Zhang1,Xian-Cang Ma3,Ya-Min Liu1,Zhi Hu1,Hong-Mei Wan1,Yu-Shun Zhang1 1.Department of Cardiovascular Medicine;2.Department of Gynecology and Obstetrics;3.Department of Psychology and Psychiatry,the First Affiliated Hospital,Medical School of Xi'an Jiaotong University,Xi'an 710061,China;Comparative study on ghrelin level change and its related factors in hypertensive elders with psychological distress[J];西安交通大学学报(英文版);2010-03
4 LI Hongxia;JIN Shenghua;GU Xuan;School of Psychology, Beijing Normal University;State Key Laboratory of Cognitive Neuroscience and Learning;;The Application of Functional Neuroimaging in the Study of Adolescents with Internet Addiction[J];Chinese Journal of Special Education;2013-11
5 ZHU Ye;FANG Jing;ZHANG Bei;LUO Ying-zi;ZHAO Wei;WANG Xiang;Medical Psychological Institute,Second Xiangya Hospital,Central South University;;Functional Neuroimaging of Social Cognition in Schizophrenia[J];Chinese Journal of Clinical Psychology;2014-02
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