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《Chinese Science Bulletin》 2014-22
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Advances in in vitro detection of cytotoxicity induced by silver nanoparticles

ZHU LingYing;GUO DaWei;GU Ning;Jiangsu Key Laboratory for Biomaterials and Devices, State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering,Southeast University;Suzhou Key Laboratory of Biomedical Materials and Technology, Research Institute of Southeast University in Suzhou;  
Silver nanoparticles(AgNPs) are widely used in the fields of biology and medicine because of their excellent optical, electrical and antimicrobial properties. AgNPs can induce cytotoxicity in various cells and organisms, which might be helpful to combat diseases. However, the biohazardous nature of AgNPs is a serious concern. More studies that focus on evaluation of the cytotoxicity of AgNPs are needed so that we can use AgNPs more effectively and minimize their toxicity. Recently, many methods to investigate the in vitro cytotoxicity of AgNPs have been reported. This paper reviews the important progress in this field to act as a reference for further AgNP experiments in vivo and in clinical settings.
【Fund】: 国家重大科学研究计划(2011CB933503)资助
【CateGory Index】: R114
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