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《Journal of Clinical Otorhinolaryngology Head and Neck Surgery》 2010-13
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The clinical significance of ABR testing in the diagnosis of the large vestibular aqueduct syndrome

HAO Jianping ZHAO Yan YAN Wenfei SHI Tianxiang (Department of Otorhinolaryngology,Rehabilitation Center Hospital of Gansu Province,Lanzhou,730000,China)  
Objective:To analyse the clinical audiological significance in the diagnosis of large vestibular aqueduct syndrome(LVAS)by the auditory brain stem response(ABR) testing.Method: Patients with sensorinenural hearing loss were examined by temporal bone CT scaning from January,2008 to September,2009.The result of CT scanning of 70 cases inner ear malformation were analysed.Patients were devided into two groups,LVAS group including 38 cases(76 ears)and other inner ear malformation group including 32 cases(62 ears).All patient accepted clinical audiology analysis and auditory brainstem respone(ABR) test.Result: Twenty-four cases(41 ears) of LVAS group were detected with ASNR in 2~3 cm by the ABR testing,the positive rate was 54%,while ASNR was not detected in patients of other inner ear malformations group.There was significant differences(P=0.01)of the ASNR between two groups.Conclusion:There is high incidence of LVAS on the patients with Non-syndromic deafness.ASNR by ABR testing could help diagnosing the LVAS.
【Fund】: 甘肃省自然科学基金项目(No:096RTZA020)
【CateGory Index】: R764
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