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《Journal of Clinical Pulmonary Medicine》 2005-01
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The study on the serological association between Chlamydia pneumoniae infection and some respiratory diseases

CHEN Yanbin TAO Yueduo LING Chunhua Department of Respiratory Disease.The First Affliated Hospital of Suzhou University,Suzhou 215006,China  
Objective To investigate the serological association between chlamydia pneumoniae(CPn)infection and some kinds of respiratory diseases such as lung cancer,chronic obstructive pulmonary disease(COPD),bronchial asthma,and so on.Methods Cpn-specific serum IgA,IgG,IgM antibodies were measured by indirect-immunofluorescence test. Results The prevalence of past and chronic CPn infection in patients with lung cancer,COPD and bronchial asthma was higher than that in the healthy bolld donors and spontaneous pneumothorax(P0.05).There were no statistical difference among lung cancer,COPD and bronchial asthma groups.The statistical difference was not found between healthy blood donors and spontaneous pneumothorax groups(P0.05).Conclusion There was suggestive evidence of a stronger association between the specific serum IgA,IgG and lung cancer,COPD,bronchial asthma at CPn infection.The chronic infection may be involved in the pathogenesis of such diseases.
【CateGory Index】: R56;R518
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