Immunohistochemical Study of Antigen Presenting Cells in The Gingiva of Periodontitis in Old Age
Gingiva tissue from 12 cases of old periodontitis patients and 9 cases of adult periodontitis and 5 cases of old persions with healthy gingiva have been stained im-munohistochemically with a monoclonal anti T6, HLA -DR antibodies to aid in the identification and quntification of langerhan's cell and macrophage. The results showed that langerhan's cell located in the poly gonal cells layer and basal cells layer of gingiva, while macrophage located in the connective tissue. The difference of langerhan's cell and macrophage between old age periodontitis and adult periodontitis was very significant. The results suggest that macrophage play an important role in the immunol regulatory of old age periodontitis; langerhan's cell play a crucial part in that of adult periodontitis.