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The Elementary Evaluation for Combination Chemotherapy With High Dosage DDP Prior to Operation for Mouth Cavity Mocosa Squamous Cell Cancer

Ye Maochang  
In this paper, 34 patient's Clinic date of combination Chemotherapy with high dosage DDP, PYM and VCR(PVP) priorto operation for mouth cavity mucosa squamous cell cancer, including strict hydration and diuresis measures, are reported. A therapy course consisted of six days, After 21 days treatment, the outcome of therapy was evaluated and then the operation was performed, of the 34 patients, 5 had a complete remission, 24 a partial response and 5 no response, yielding a 85.29% Overrall response rate (29 of 34), Authors' study in volved with the scheme for DDP and PVP and its basis, The prevention and treatement for poisonous-ness sideeffect appeared in the therapy process and its clinic significance have also been discussed, The results show that DDP has important the rapy value for 'mouth cavity mocosa squamous cell cancer and its effect is concerned with the increment of dosage.
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