The content and roles of enzymes and MDA in saliva of patients with periodiontitis induced by Entamoeba gingivalis.
Liu Guangying,Chen Jinfu, et al. Department of Parasitology, Fujian Medical University, Fuzhou 350004.
Objective To explore the roles of enzymes and oxygen free radicals in periodontitis induced by Entamoeba gingivalis(Eg). Methods The subjects were divided into three groups: 13 patients with periodontitis induced by Eg ,9 patients with periotontitis who hadn't been infected with Eg, 9 healthy persons as the control group. The activity of superoxide dismutase (SOD)、acid phosphatase (ACP) and catalase (CAT) and content of maldondialdehyde (MDA) in saliva were detected individully with biochemical methods. Results Statistical analyses of the data showed: The SOD activity in patients with periodontitis induced or not by Eg was lower than the control group; The ACP activity and MDA level in patients with periodontitis induced by Eg were higher than the other two groups; There were no difference in the CAT activity among three groups. Conclusion It is one of the pathogenetic mechanisms of periodontitis induced by Eg that ACP and oxygen free radicals destroy the plasmalemma and membranous organelles, which hurt the host's epithelial cells in gingival tissue.