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Correlativity of the chronic periodontitis with helicobacter pylori infection.

GAO Jing1,ZHU Sheng-rong2,LIU Xian1,LI Yue-xiu3,WANG Yan-chun3.1.Department of Stomatology,Tongji Hospital of Tongji Medical College;Huazhong Univesity of Science and Technology,Hubei Wuhan 430030,China.2.Department of Neurology,Affiliated Hospital of Medical College,Qingdao Univesity,Shangdong Qingdao 266003,China 3.Department of Stomatology,Ttaian Central Hospital,Shangdong Taian 271000,China  
Objective:To investigate the relationship between Helicobacter pylori(Hp) and periodontitis.Method:A polymerase chain reaction(PCR) assay with oligonucleotide primers homologous to a portion of the u-rease C and cytotoxin-associated gene A(cagA) ofHpwas used to test for the presence ofHpin dental plaque.Thirty-seven patients with periodontitis and 38 healthy persons were studied to compare the results of the two Groups.Result:In the periodontitis group,64.8 % f the tested samples was ureasc gene positive,and 32.4 % was positive for both urease C and cagA genes.In healthy persons,38.5 % of the tested samples was urease C gene posi-tive and 7.7 % was positive for both urease C and cagA genes.There was a significantly difference between the twogroups(P 0.01).The Hp-positive rate of the major periodontitis was enhanced obviously to minor peciodontitis.The Hp-positive rate of subgingival plaque was significantly higher than that of supragingival plague.Conclusion:HP participates the formation of the chronic periodontitis or it increases the pathogenic effect of other factors.
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