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《Journal of Clinical Stomatology》 2014-10
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Clinical analysis of Candida infection in oral leukoplakia

XU Zi-yuan;WEI Ben-juan;SHI Lin-jun;ZHOU Zeng-tong;Department of Stomatology,Renji Hospital,School of Medicine,Shanghai Jiaotong University;Department of Oral Mucosal Diseases,Ninth People's Hospital,School of Medicine,Shanghai Jiaotong University;  
Objective:To study the clinical and pathological features of Candida infection in oral leukoplakia.Method:Candidal hyphae were detected with periodic acid-Schiff staining of the biopsy samples from a retrospective series of 448 cases of patients with oral leukoplakia,and analyze the relationship between age,sex,location,and epithelial dysplasia and infection. Result:Of them,63 patients(16.4 %)with oral leukoplakia were infected by Candida. Candidal leukoplakia was highly associated with dysplasia compared to common type(57.1 % vs. 33.8 %). Regression analysis showed that 60years,tongue and dysplasia are predisposing factors. Conclusion:Candida infection correlated with dysplasia. Elderly patients with tongue leukoplakia with dysplasia had much higher risk of candidal infection.
【Fund】: 上海市重点学科建设项目(s30206)
【CateGory Index】: R781.5
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