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The effects of garlic, hydrogen peroxide and citric acid on the ultrastructure of oral anaerobes

Li Deyi, etal. The Ninth Hospital, Shanghai Second Medical University, Shanghai(200011)  
Aim In order to investigate the bactericidal mechanism of garlic (G), hydrogen peroxide (H) and citric acid (C). Methods Their effects on the ultrastructure of porphyromonas gingivalis (Pg), Bacteroides fragilis (Bf) and Fusobacterium nucleatum (Fu) were observed by scanning electron microscopy. Resuts After oral anaerobes were exposed to G, H and C at 37℃ for 15 minutes, the ultrastructure changes of anaerobes differed in degree. Their cell wall, membrane were ruptured, thinned or disappeared, and the cell plasma was degenerated, such as ribosome aggregation, enzyme precipitation or plasma solution etc. Conclusions This study observed the effects of G, H and C on the ultrastructure of oral anareobes and supplied bactericidal mechanisms of drug.
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