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《Chinese Journal of Clinical Neurosciences》 2018-03
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Review on the Research Progress of Chronic Migraine Animal Model

REN li;ZHU Ting;ZHANG Yan-lin;LUO Wei-feng;Department of Neurology,the Second Affiliated Hospital of Soochow University;  
Chronic migraine is a disabling disease affecting hundreds of millions of people.So far there is no ideal specific prevention and treatment drug.The slow development of the treatment measures is due to the lack of an effective animal model.The ideal chronic migraine animal model should be able to restore its key pathophysiological mechanisms.Because of the similar pathophysiology of chronic migraine and episode migraine,animal models of chronic migraine mostly draw lessons from the animal model of migraine,Successful models provide a pathophysiological mechanism for the study of episode migraine into chronic migraine.This article elaborates the research status of chronic migraine animal model in recent years from the aspects of animal model principle,modeling method and model features.
【CateGory Index】: R-332;R747.2
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