Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Practical Clinical Medicine》 2000-01
Add to Favorite Get Latest Update

Lowdose Cyclosporin A in the Treatment of Aplastic Anemia

YANG Biyun,LI Huihui,SHI Qingzhi,CAO Ruisheng,TANG Aiping,HUA Jianyuan (The Second Affiliated Hospital Jiangxi Medical college Nanchang 330006)  
Objective:To explore the efficacy of lowdose cyclosporin A (CsA) and the factors of pridicted effect in the treatment of aplastic anemia (AA).Methods:Thirtysix cases of AA were treated with lowdose CsA (6 mg/kg/d,10 d;3 mg/kg/d,3 m).Results:A response was achicved in 26 of 36 patients with AA (72%).The effect was rclated with the sex of patients and the results of CsA testing in vitro.The response rate of male cases was higher than that of female cases.Seven cases were positive in the CsA testing in vitro and were all responsed to CsA;Seventeen cases were negative,nine cases of which were responsed to CsA (p=0.03).Conclusions:(1)Lowdose CsA can be used in the treatment of all kinds of AA;(2)The CsA testing in vitro can be used to predict the response of some patients with AA.
【CateGory Index】: R556.5
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 4 Hits
1 YANG Bi yun,XIONG Hong,LIAO Yi xiang,Li Hui hui (Department of Hematology,Second Affiliated Hospital,Jiangxi Medical College,Nanchang 330006,China);The Pathogenesis of Aplastic Anemia and the Influence of Cyclosporin A on Aplastic Anemia in Vitro[J];ACTA ACADEMIAE MEDICINAE JIANGXI;2000-01
2 Shao Zonghong,Chen Keqi,Chen Guibin,et al.Institute of Hematology and Blood Diseases Hospital, CAMS and PUMC, Tianjin 300020;Correlation between the serum levels of interleukin 2 and soluble interleukin 2 receptor and the response to immunosuppressive therapy in severe aplastic anemia patients[J];CHINESE JOURNAL OF HEMATOLOGY;1997-04
3 Shao Zonghong, Zheng Yizhou, Zhang Yizhi, et al. Institute of Hematology and Blood Diseases Hospital, CAMS and PUMC, Tianjin, 300020;Treatment of chronic aplastic anemia with triolandren and cyclosporin A[J];CHINESE JOURNAL OF HEMATOLOGY;1998-04
4 ZHENG Yizhou,CHU Yulin, SHAO Zonghong, et al. Institute of Hematology and Blood Diseases Hospital, CAMS and PUMC, Tianjin 300020;Antilymphocyte globulin combining with cyclosporine A in the treatment of severe aplastic anemia[J];CHINESE JOURNAL OF HEMATOLOGY;1999-04
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 zhang Guoxiang,Han Yumei Department of Hematology,Heping Hospital;The Observation on the effect of CsA on the Treatment of AA[J];Journal of Changzhi Medical College;2004-02
2 Zhang Guoxiang Department of Hematology,Heping Hospital;ALG and CsA on rteatment for Severe Aplastil Anemia[J];Journal of Changzhi Medical College;2004-04
3 YU Fang, TANG Suo-Qin, WANG Jian-Wen. Department of Pediatrics, General Hospital of People's Liberation Army, Beijing 100853, China;Therapeutic effect of antithymocyte /antilymphocyte globulin on severe aplastic anemia and therapy-related complications[J];Chinese Journal of Contemporary Pediatrics;2006-06
4 LI Shou-she,KOU Yi,SONG Bai-song,et al.Department of Hematology,Shandong Goal Mineral General Hospital,Jinan,250022,China;Combinative Study for Treatment of Aplastic Anemia of Securinine Plus Anisodamini Dripping in Bone Marrow[J];Journal of Chinese Physician;2003-S1
5 HUAN Shuhuang CAI Chengcai WU Jinquan et al. The 1th People's Hospital of Zhaoqing,Zhaoqing,526021;Clinical analysis of 41 cases with apiastic anemia[J];International Medicine & Health Guidance News;2006-01
6 Zhu Zhigang, Mao Ping, Ying Yi, et al. Department of Hematology, Guangzhou First Municipal People's Hospital, Guangzhou 510180;Conditioning with antithymocyte/antilymphocyte globulin for allogeneic stem cell transplantation[J];Guangzhou Medical Journal;2000-04
7 Huang Shuhuang,Cai Chengcai,Wu Jinquan,et al.The First People's Hospital of Zhaoqing,Zhaoqing,526021;Clinical analysis of 41 cases with apiastic anemia[J];Guangzhou Medical Journal;2005-01
8 SONG Chun-ming,JIANG Jie,LI Jian-hua (Department of Traditional Chinese Medicine,Affiliated Hospital of Weifang Medical College,Weifang 261031,China);Clinical Observation of Caffeic Acid Combined with Cyclosporine,Androgen Treatment of Anemia Aplastic Anemia[J];Journal of Hubei University for Nationalities(Medical Edition);2009-03
9 DONG Jian-ming,XU Hao,FANG Fu-hai,et al (The First People's Hospital of Yancheng City,Jiangsu Yancheng 224001,China);Observing the effect of cyclosporine A combined androgen on chronic aplastic anaemia[J];Hebei Medicine;2006-11
10 BAI Xiao-chuan,GUO Hong-wei,YANG Guo-zhen,et al. (Department of Hematology,Affiliated Hospital of Ningxia Med.Coll,Yinchuan 750004,China);The Effectiveness of Home-made Cyclosporin A Regime in the Treatment of Aplastic Anemia[J];West China Medical Journal;2003-03
【Secondary Citations】
Chinese Journal Full-text Database 3 Hits
1 SHAO Zong-Hong ZHENG Yi-Zhou ZHANG Yi-Zhi CHEN Gui-Bin LI Li SUN Juan CHU Yu-Lin (Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300020);Changes of Marrow Hematopoietic Progenitor Cells in Patients with Severe Aplastic Anemia after Intensive Immunosuppressive Therapy[J];Journal of Experimental Hematology;1997-04
2 ShaoZonghong,ChuYulin,ZhangYizhi,etal.InstituteofHematology,CAMS&PUMC,Tianjin,300020;TreatmentofsevereaplasticanemiawithALG/CSAwithorwithoutGM┐CSFandEpo[J];CHINESE JOURNAL OF HEMATOLOGY;1996-04
3 ZHENG Yizhou,CHU Yulin, SHAO Zonghong, et al. Institute of Hematology and Blood Diseases Hospital, CAMS and PUMC, Tianjin 300020;Antilymphocyte globulin combining with cyclosporine A in the treatment of severe aplastic anemia[J];CHINESE JOURNAL OF HEMATOLOGY;1999-04
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved