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《Chinese Journal of Clinical Medicine》 2006-01
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Experence of A New Abdominal Cardiac Transplantation Model in Rats

LIU Fabing LIU Zhihong TAN Jianming, et al.Department of Renal Transplantation,Shanghai First People's Hospital; Shanghai Clinical Medical Center of Organ Transplantion,Shanghai 200080  
Objective:To establish an improved heterotopic cardiac transplantation model in rats. Methods:Sprague Dawley rats have been used as recipients and Wistar rats as donors. Donor aorta was anastomosed to the recipient's suprarenal abdominal aorta;donor pulmonary artery was anastomosed to the left renal vein of the recipient using continuous suture technique The operation was considered be successful if the recipient rat and graft survive over 3 days. They were compared with models performed using modified Ono procedure Results: Forty rats of heterotopic cardiac transplantation were performed using new procedure and twenty were performed using modified Ono procedure, with successful rate 92. 5% and 75% respectively. Mean time of ischemia and operation was both significantly shorter in rats using new procedure than that of rats using modified Ono procedure The rate of complications in rats using new procedure was significantly lower. Conclusion:The method is easy,quick and reliable, which has a low incidence of morbidity and mortality. The model perhaps is more suitable for heterotopic heart transplantatioa
【Fund】: 上海市卫生局青年科研基金资助项目(044Y20)
【CateGory Index】: R-332;R654.2
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【Citations】
Chinese Journal Full-text Database 1 Hits
1 CHEN Jian-feng, GAO Yi, SUN, Er-wei, WANG Shuang (Department of Organ Transplantation, Zhujiang Hospital, First Military Medical University, Guangzhou 510282, China);Modification of a rat heterotopic heart transplantation model[J];Journal of First Military Medical University;2001-09
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 CHEN Jian-feng, GAO Yi, SUN, Er-wei, WANG Shuang (Department of Organ Transplantation, Zhujiang Hospital, First Military Medical University, Guangzhou 510282, China);Modification of a rat heterotopic heart transplantation model[J];Journal of First Military Medical University;2001-09
2 Yang Shangqi, Cai Xian - an , Xia Suisheng, et al .Department of Urology , Shanghai First People's Hospital, Shanghai 200080;Prolongation of Rat Cardiac Allograft Survival by Donor Antigen Specific T Cell vaccination[J];Henan Journal of Surgery;2001-03
3 ZHANG Yongke, ZHAO Gaofeng, QIAO Chenhui, YANG Chenyuan, ZHI Xingyi Department of Cardiothoracic Surgery,the Affiliated Union Hospital, Tongji Medical College , Huazhong U-niversity of Science and Technology, Wuhan 430030 Department of Cardiothoracic Sur;Effects of β-AESCIN on myocardial cell apoptosis induced by reperfusion after heart transplantation in rats[J];Journa of Henan Medical University;2002-01
4 ZHANG Yongke 1) ,WANG Aiping 2) ,YANG Chenyuan 1) ,FU Fengying 3) 1)Department of Cardiovascular Surgery,the Affiliated Union Hospital, Tongji Medical College,Huazhong University of Science and Technology Wuhan 430030 2) Department of Cli;Protective effects of exgenous creatine phosphate on donor heart preservation for rats[J];Journa of Henan Medical University;2002-02
5 ZHAO Yilei 1), GAO Yingxin 2), LI Jianhui 3) 1)Department of Radiology, the First Affiliated Hospital, Zhengzhou University, Zhengzhou 450052 2)The Fourth Department of Internal Medicine, Electricity Power Hospital of Henan Province, Zhengzhou 450006 3)Department of General Surgery,the First Affiliated Hospital,Shihezi University,Shihezi 832008;Two-cuff technique for heterotopic heart transplantation in rats[J];Journal of Zhengzhou University(Science Medical);2005-02
6 ZHANG Yongke 1),LIU Changfa 2) 1)Department of Cardiothrocic Surgery, the Seventh People's Hospital of Zhengzhou, Zhengzhou 450006 2)Department of Pharmacology,Zhengzhou Railway Professional Technological College,Zhengzhou 450052;Experience of the heart heterotransplantation in 150 rats[J];Journal of Zhengzhou University(Science Medical);2005-03
7 KOU Yinglin,ZHAO Wenzeng.The First Affliated Hospital of Zhengzhou University,Zhengzhou 450052,China;Some improvements in establishing Ono's heterotopic heart transplant model[J];Journal of Practical Diagnosis and Therapy;2006-02
8 JIN Zhong-da, CHEN Jiang-hua Nephropathy Center of the First Affiliated Hospital of Medical College of Zhejiang University, Hangzhou 310003, China);Improved technique of heterotopic heart transplantation model in rats[J];Journal of Regional Anatomy and Operative Surgery;2004-03
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10 LI Jing lai 1, XIAO Ming di 1, YANG Chen yuan 2 (1. The Clinical Medicine Postdoctoral Station of Fudan University, Department of Cardiovascular Surgery, The First People's Hospital, Shanghai 200080,China; 2. Department of Cardiovascul;Establishment and Development of the Rat Heterotopic Heart Transplantation Model[J];Shanghai Laboratory Animal Science;2001-03
【Secondary Citations】
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