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《Chinese Journal of Clinical Medicine》 2006-01
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Surgical Treatment for Cardiovascular Abnormalities Related to Marfan Syndrome

LI Chunhua WANG Wujun CAI Kaican,et al.Department of Cardiothoracic Surgery,Nan fang Hospital,Nanfang Medical University,Guangzhou 510515  
Objective:To report our 10-year experience of surgical treatment with 40 Marfan patients for cardiovascular abnormalities. Methods:From July 1995 to December 2001, 40 consecutive Marfan patients with cardiovascular abnormalities (30 males) underwent surgical treatment. 34 patients had a modified Bentall procedure ("button" technique), 3 patients underwent a Cabral technique, one patient had a valve-sparing procedure, one patient underwent a modified Bentall procedure and a concomitant total arch replacement, one patient had a modified Bentall procedure and a concomitant total arch replacement and "elephant trunk"technique. Mean age was 39. 0±13.7 years. Results:There was no 30-day death 16 patients occurred early complications (40%). Of these complications, respiratory dysfunction was most frequent. Mean follow-up time was 35±17 months (4 months to 9 years). One patient died suddenly 3 years after operation.Statistical analysis revealed that preoperative acute symptom was significant risk factor of early complications. Conclusion:Aortic root replacement with a composite graft is a safe procedure in Marfan patients with cardiovascular abnormalities. The "button" technique offers some advantages and should be used whenever possible. Elective repair when the aortic root reaches 5 cm in diameter is recommended to minimize risk of dissection and rupture
【CateGory Index】: R654.2
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