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《Chinese Journal of Clinical Medicine》 2006-01
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The Clinical Study on Bronchofibroscope Lavage Treatment to Mechanical Ventilation Related Pulmonary Infection

ZHANG Yongli WAN Xianyao. Central Intensive Care Unite,The First Affiliated Hospital of Dalian Medical University,Dalian 116011  
Objective: To observe the therapeutic effect of bronchofibroscope lavage for serious pulmonary infection caused by mechanical ventilatioa Methods: All of 28 severe patients of pulmonary infection were performing mechanical ventilation because of I-type orⅡ-type respiratory failure They all accepted the treatment of bronchofibroscope lavage under the monitoring of ECG, blood pressure and blood oxygen saturation.Mean while, the antibiotics and apophlegmatic drug were used too. The index we used to evaluate the therapeutic effect include the change of body temperature, quantity and quality of sputum, bellows auscultation, breath sound changing of pulmonary atelectasis, saturation of blood oxygen, blood gas analysis and chest xray. Results: The staying days in ICU of all 28 cases were 2-63d, the mean was 24. 5d, 1-6 bronchofibroscope lavage treatments were performed, the mean was 2. 4. Compared to prior treatment ,the SaO2 (93±5% vs 86 ±4%, P0. 05)and PaO2 (87±8 mmHg vs 68±10 mmHg,P0. 05)increased , PaCO2(37±7 mmHg vs 48±9 mmHg,P0. 05)decreased significantly. After bronchofibroscope lavage treatment, 25 patients with pulmonary infection were controlled, all 4 cases with pulmonary atelectasis were completely recovered. But the body temperature, quantity and quality of sputum, bellows auscultation and chest X-ray of 3 patients did not improve obviously because of their primary disease aggravation. No complications such as aeropleura and respiratory tract bleeding occurred. Conclusion: Bronchofibroscope lavage treatment can be an effective way to control severe pulmonary infection caused by mechanical ventilation in intensive care unite
【CateGory Index】: R563.1
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