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《Chinese Journal of Clinical Medicine》 2006-01
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Photodynamic Therapy for Macular Circumscribed Choroidal Hemangioma

ZHANG Yongjin WANG Wenji LI Lei, et al. Department of Ophthalmology,Eye and ENT Hospital,Fudan University, Shanghai 200031  
Objective:To evaluate the efficacy and safety of photodynamic therapy (PDT) in patients of macular choroidal hemangioma.Methods:Five patients,the visual acuity was 0.04-0.5,were diagnosed as choroidal hemangioma in macular area clinically presenting with serous retina detachment 0.5-4mm and with a retinal cyst in 1 case. The hemangioma was 2. 5-3. 8mm in thicness and 7. 7-9.4 mm in largest dimension measured by B ultrasound,Photodynamic therapy was performed with a concentration of verteporphin 6mg/m2 body surface area and laser parameter 50-75 J/cm2,83-125s at 689 nm, 2-5.4 mm in size,1-2 spots. All were treated with one sessioa The follow up time is 15-28 weeks. Results: Visual acuity was 0.04-1.0 in last examination. The hemangioma was undetectable in 2 cases and 0. 7-3.0 mm in thickness and 7.6-8.6 mm in largest dimension in other 3 cases. Retina detachment was disappeared in all cases but one remain 1mm retinal detachment with the retinal cyst vanished. Conclusion: PDT is effective and safe to reduce the choroidal melanoma size , eliminate the subretinal fuild and improve or stable the visual acuity of the patient with tumor under macular area.
【CateGory Index】: R774.5
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【References】
Chinese Journal Full-text Database 1 Hits
1 Peng Zhang,Yu-Sheng Wang,Hai-Yan Wang,Dan Hu,Zhu-Ning He,Jing Bai,Zi-Feng Zhang,Xiao-Na Su,Jian-Wei BaiDepartment of Ophthalmology,the Fourth Military Medical University,the Eye Institute of Chinese PLA,Xi'an 710032,Shaanxi Province,China;Indocyannine green mediated photothrombosis for circumscribed choroidal hemangioma[J];International Journal of Ophthalmology;2008-08
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【Co-citations】
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1 WANG Lin-li,MENG De-sheng(Department of Pharmacy,Daping Hospital,Third Military Medical University,Chongqing 400042,China);Clinical development of subhyaloid hemorrhage[J];Food and Drug;2006-04
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【Secondary References】
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1 Peng Zhang,Yu-Sheng Wang,Hai-Yan Wang,Dan Hu,Zhu-Ning He,Jing Bai,Na Ni Department of Ophthalmology,Eye Institute of Chinese PLA,Fourth Military Medical University,Xi'an 710032,Shaanxi Province,China;Therapy of Indocyannine green mediated photothrombosis for idiopathic choroidal neovascularization[J];International Journal of Ophthalmology;2008-11
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