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《Chinese Journal of Clinical Medicine》 2006-01
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Flora Distribution and Analysis of Drug Resistance of the 4754 Clinical Isolated Bacteria Strains

KONG Fan- glin CHUCongjia GUAN Xinlong,et al. Dpartmen of Laboratory Medicine,Yuxi City People's Hospital in Yunnan Province Yuxi 653100  
Objective:To study the flora distribution and investigate drug resistance of clinical isolated bacteria in Yuxi city for the guidance of rational use of antibiotics. Methods: A retrospective analysis was made on a total of 4754 strains of pathogens separated from blood, body fluid, urine, sputum, vaginal secreta and stool samples from 1999 to 2001 years in Yuxi municipal people's hospital. Results: The proportion of Gram-negative bacilli rose obviously, so did the opportunistic pathogen's and Yeasts detected rate. Most drug sensitive tests showed the drug-fast rate turned to be high.Escherichia coli, Salmonella and Citrobacter resistant and so on to fluoroquinolones was 57%-97%. These bacteria to imipenem showed excellent activity. Meticillin-resistant-staphylococcus (MRS) resistant to ciprofloxacin, norfloxacin, clindamycin, tetracycline, erythromycin, ce fazolin and ampicillin were 40.9%, 42.4%, 63.6%, 72. 2%, 85. 9%, 100. 0% and 100. 0%, respectively Streptococcus and Enterococcus resistant to major β-lactams-penicillin,aminoglycosides, macrolides, tetracyclines and sulfonamides were between 36.0% to 100.0%. Conclusion:The situation of clinical antibiotic resistance is quite serious, the bacteria's drug resistance dynamics in our responsible region should examine constantly, so to guide doctors using drugs reasonably.
【CateGory Index】: R446.5
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