Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of Clinical Medicine》 2006-02
Add to Favorite Get Latest Update

The Effect of Noninvasive Positive-Pressure Ventilation on Arterial-blood Gas in Patients with Severe Respiratory Failure

OUYANG Xiuhe YU Liping ZHENG Wentao et al.Department of Respiratory Disease,Bin zhou Municipal People's Hospital in Shandong Province,Binzhou 256610  
Objective:We conducted a prospective, randomized trial of BiPAP noninvasive positive-pressure ventilation as compared with endotracheal intubation or tracheotomy with conventional mechanical ventilation in patients with severe respiratory failure who required mechanical ventilation, and the arterial-blood gas value improvement was compared. Methods: According to the arterial-blood gas value, and consciousness determined at baseline, severe patients of COPD with respiratory failure were included. Patients were assigned into treatment group control group, the treatment group were received noninvasive ventilation, and control group were treated with conventional mechanical ventilation. Medical management for the conditions, which consist of anti-infection, and general medical therapy, ect, were similar in the two groups. All patients underwent continuous electrocardiography and monitoring of arterial oxygen saturation. Arterial-blood gas value were determined at baseline, at 2-3 hour, at six-hour, 24-hour and 72-hour intervals during mechanical ventilation, and before discontinuation of ventilatory support. Consciousness, breathe, heart rate, blood pressure were observed during the treating period. Results: 52 patients were enrolled in the study 29 in the treatment group,while 23 in the wound group. In treatment , 2 subjects quit treatment required by his family, 2 subjects switched to endotracheal intubation and convention al ventilatilation , 1 died,, the other 24 subjects recoverd after noninvasive ventilation. The length of ventilation was 7.6±5.4d,the time of consciousness recover was 4. 8±3. 8(2-22)hour,the length of stay in the hospital was 13. 3±5. 8d. In control group, 6 cases were noninvasive ventilated for refusal of endotracheal intubation, 2 subjects quit treatment, 2 died, 13 subjects recovered after conventional mechanical ventilation. The length of ventilation was 6.5±6.2d ( vs treatment group, P0.05), the time of consciousness recover was 4.5±2.6(2~11)hour ( vs treatment group, P0. 05),the duration of stay in the hospital was 12. 2±8. 8d ( vs treatment group, P0.05). The patients in the two groups had a similar initial change in PaO2:FiO2,PaCO2 and heart rate . 4 patients facial-skin breakdown (especially at the bridge of the nose), 5 cases gastric distention in treatment group. While 4 patients had ventilator-associated pneumonia, 4cases had gastric distention in control group. Conclusion: We found that noninvasive ventilation was as effective as conventional ventilation, especially in improving gas exchange in patients with sever respiratory failure, and was associated with fewer serious complications that ventilator-associated pneumonia.
【CateGory Index】: R563.8
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 2 Hits
1 Jin Xiaoyan Xia Jisen (Department of Pulmonology, Changning Central Hospital, Shanghai 200336);The Value and Limitation of Noninvasive Pressure Support Ventilation in Patients with Respiratory Failure[J];Clinical Medical Journal of China;2002-06
2 Niu Shanfu (Zhongshan Hospital and Institute of Respiratory Disease, Fudan University, Shanghai 200032;The Advances of Mask Mechanical Ventilation in the Treatmeat of Respirative Failure[J];Clinical Medical Journal of China;2003-05
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 TANG Jie,SHEN Ce(Department of Respiration,the Sixth People's Hospital of Shanghai,Shanghai 200233);Analysis of the effect and economics of no-invasive positive-pressure ventilation(NIPPV)in treating chronic obstructive pulmonary diseases(COPO) acute exacerbation[J];Beijing Medical Journal;2007-11
2 ZHANG Yu-mei The Fifth Hospital of Guilin City,Guilin 541004,China;Clinical study on treatment of acute cardiogenic pulmonary edema by noninvasive mechanical ventilation[J];Acta Medicinae Sinica;2008-01
3 LI Zi-jie,KONG Xiang-wei.Department of Respiratory Medicine,The People's Hospital of Huaiji,Huaiji 526400,China;The application of plateau expiratory valve in the Non-invasive positive ventilation[J];International Journal of Internal Medicine;2007-08
4 JIN Tao,TIAN Zhuomin. Department of Intensive Care Unit, Tianjin City Hospital, Tianjin 300121,China;Non-invasive positive pressure ventilation in treating acute respiratory distress syndrome[J];Journal of Clinical Pulmonary Medicine;2007-01
5 LI Hai-ling, LIU Hong, LIN Hui-yan, et al. The ICU of the 401st Hospital of PLA, Qingdao 266071,China;Clinical study of non-invasive management with bi-level positive airway pressure ventilation in elderly patients with acute left heart failure[J];Practical Journal of Medicine & Pharmacy;2007-04
6 CHEN Zengrui,ZHENG Xiaojin,ZHOUZhaoyang,GAN Yongxiong.Yuhuan People's Hospital,Yuhuan317600,China;Clinical study of non-invasive positive pressure ventilation in the treatment of 36 patients with acute cardiogenic pulmonary edema[J];Clinical Education of General Practice;2006-03
7 Chen Zhuangsheng. (Pinghu People’s Hospital,Shenzhen Longgang,Guangdong 518111 China);Clinical Analysis of Bi-level Airway Pressure Ventilation (BiPAP) Breathing Apparatus in the Type Ⅱ Respiratory Failure of Chronic Obstructive Pulmonary Diseases (COPD)[J];Journal of Qiqihar Medical;2005-04
8 LIU Ji-ning,YANG Yong,LV Ru-qi.Department of Emergency,Central Hospital of Mianyang,Mianyang,Sichuan 621000,China;The effect of BiPAP in blood gas to the patients with tape Ⅱ respiratory failure in emergency treatment[J];Sichuan Medical Journal;2008-05
9 ZAN Hai-feng1,XU Zhi2,YANG Xun1.1.Chengdu Railway Center Hospital,Chengdu,Sichuan 610081,China;2.Xin Qiao Hospital Of Third Military Medical University,Chongqing 400038,China;Noninvasive positive pressure ventilation in the patients with acute respiratory distress syndrome[J];Sichuan Medical Journal;2009-02
10 Zhuang Lihua(Minhang Hospital of Ruijin Hospitals Group of Shanghai City, Shanghai 201100 China);Nursing progress on mechanical ventilation oxygen therapy via mask[J];Chinese Nursing Research;2006-17
【Secondary Citations】
Chinese Journal Full-text Database 7 Hits
1 LI Haichao 1, NIE Ligong 1, WANG Guangfa 1△ , QUE Chengli 1, MA Jing 1, LI Nan 1, ZHAO Zhijie 1, GAO Zhidong 2, XV Xiaoyuan 1, LU Haiying 1 (1.Peking University First Hospital, Beijing 100034, China; 2. Peking University School of Public Health);Clinical observation of non-invasive positive pressure ventilation (NIPPV) in the treatment of Severe Acute Respiratory Syndrome (SARS)[J];Journal of Beijing Medical University;2003-S1
2 Niu Shanfu, Zhu Lei, Cai Yingyun, Bai Chunxue, Li Yanqin(Institue of Respiratory Diseases, Department of Pulmonology Diseases, Zhongshan School of Clinical Medicine,Shanghai Medical University, Shanghai 200032);THE INFLUENCE OF VENTILATING TECHNOLOGY TO THE FACE MASK MECHANICAL VENTILATION IN COPD PATIENTS WITH RESPIRATORY FAILURE[J];JOURNAL OF SHANGHAI MEDICA(UNIVERSITY);1998-02
3 ZHU Lei ,RONG Weihai, NIU Shanfu ,et al. Pulmonary Department, Zfiongshan Hospital, Fudan Medical University . Shanghai 200032, China;The treatment of acute pulmonary edema via face mask mechanical ventilation[J];Chinese Journal of Respiratory and Critical Care Medicine;2002-04
4 LUO Zhe,ZHU Duming, NIU Shanfu . Department of Anesthesia, Zhongshan Hospital Fudan University. Shanghai 200032, China;Application of noninvasive positive pressure ventilation in surgical intensive care unit[J];Chinese Journal of Respiratory and Critical Care Medicine;2002-04
5 WANG Chen; SHANG Mingyu;HUANG Kewu,et al. (Beijing Red Cross Chaoyang Hospital-Beijing Institute of Respiratory Medicine,Capital University of Medical Sciences,Beijing 100020,China );Sequential non-invasive following short-term invasive mechanical ventilation in COPD induced hypercapnic respiratory failure[J];CHINESE JOURNAL OF TUBERCULOSIS AND RESPIRATORY DISEASES;2000-04
6 ZHU Lei;NIU Shanfu;LI Shanqun;et al. (Institute of Respiratory Disease,Shanghai Medical University,Ddpartment of Pulmonology,Zhongshan Haspital, Shanghai 200032, China)[;Nasal or oranasal face mask mechanical ventilation in the treatment of acute respiratory distress syndrome[J];CHINESE JOURNAL OF TUBERCULOSIS AND RESPIRATORY DISEASES;2000-04
7 LIU Xiao-qing, CHEN Si-bei, HE Guo-qing, LI Yi-min, HE Wei-qun, CHEN Rong-chang, ZHONG Nan-shan. Guangzhou Institute of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical College, Guangzhou 510120, China;Management of critical severe acute respiratory syndrome and risk factors for death[J];Chinese Journal of Tuberculosis and Respiratory Diseases;2003-06
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved