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《Chinese Journal of Clinical Medicine》 2006-02
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Efficacy of Helicobacter Pylori Eradication Treatment in Patients with Functional Dyspesia

SHI Lihua ZHANG Qisheng Department of Digestive Disease,the Branch of First People's Hospital of Shanghai,Shanghai 200081  
Objective: To evaluate efficacy of Helicobacter pylori eradication treatment in patients with functional dyspepsia infected with H pylori. Methods: According to Rome Ⅱ criterion of function dyspepsia to recruit patients. We performed a randomized, placebo-controlled trial for comparing the efficacy of treatment with omprazole amoxicillin and furozolidone(88 patients) with that of omeprazole alone(86 patients) for resolving symptoms of dyspepsia in patients with H. pylori infectioa Symptoms were assessed with modified Glasgow Dyspepsia Severity Score. One year later the patients were assessed to determine the frequency of the resolution of symptoms. Results:Dyspepsia had resolved in 23 of 88 patients(26. 13%)in the group given omeprazole and antibiotics, as compared with 9 of 86(10.46%)in the group given omeprazole alone (P0.05). The relief of symptoms in 55 of 88 patients (62. 50%) in the group given omeprazole and antibiotics was superior to the group given omeprzaole alone in 34 of 86 patients(39.53%)(P0.05). Conclusion:In patients with H. pylori infection and functional dyspepsia, treatment with omeprazole and antibiotics could eradicate the H. pylori infection and is more likely to resolve symptoms than treatment with omeprazole alone.
【CateGory Index】: R57
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【Citations】
Chinese Journal Full-text Database 1 Hits
1 LI Yi hui, ZHANG Peng bin, GUO Hong, WANG Lei, BAI Jian ying, DA Si ping, ZHAO Xiao yan (Department of Gastroenterology, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China);Effects of Helicobacter pylori eradication on functional dyspepsia[J];Acta Academiae Medicinae Militaris Tertiae;2004-11
【Co-references】
Chinese Journal Full-text Database 1 Hits
1 ZHU Jin zhao, LENG En ren, CHEN Dong feng, SHI Hong tao, GUI Xian yong (Department of Gastroenterology, Daping Hospital, Third Military Medical University, Chongqing 400042,China);A screening study of the kinetogenic effects of 15 Chinese herbal medicines on the gastrointestinal tract in rats[J];ACTA ACADEMIAE MEDICINE MILITARIS TERTIAE;2000-05
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