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《Chinese Journal of Clinical Medicine》 2006-02
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Prevalence of Hyperuricemia among Patients with Type 2 Diabetes Aged over 30 in Shanghai

LU Bin DONG Xuehong YANG Yehong et al.Department of Endocrinology,Huashan Hospital,Fudan University,Shanghai 200040  
Objective:To investigate the prevalence of hyperuricemia among the Chinese patients diagnosed with type 2 diabetes aged over 30 in Shanghai central area and evaluate the relationship between hyperuricemia and metabolic syndrome(MS). Methods: 1039 Chinese patients diagnosed with type 2 diabetes aged over 30 were investigated by randomized cluster sampling in Shanghai central area and 1008 patients were analyzed in this study. Body mass measurements, resting blood pressure, fasting blood measures were investigated. The prevalence of hyperuricemia and the risk factors associated with hyperuricemia were investigated. The relationship between hyperuricemia and metabolic syndrome (MS) was evaluated. Results:(1) Age, body mass index, waist circumference, serum triglyceride, systolic blood pressure and diastolic blood pressure in hyperuricemia subgroup were significantly higher than those in non-hyperuricemia subgroup. Fasting glucose concentration, HbA1c and HDL in hyperuricemia subgroup were lower than those in non-hyperuricemia subgroup. (2) The prevalence of hyperuricemia was 10. 0% among the Chinese patients diagnosed with type 2 diabetes aged over 30 in Shanghai central area, 11.1% with male and 9.4% with female. The prevalence of hyperuricemia in female increased following the aging. (3) The percentage of MS in hyperuricemia subgroup was significantly higher than that in non-hyperuricemia subgroup (63. 4% vs. 49. 8% ,x2 6. 660,P=0. 012). (4) Aging,obesity and lower HDL were risk factors of hyperuricemia by stepwise Logistic regression. Conclusion:The prevalence of hyperuricemia was 10. 0% among the Chinese patients diagnosed with type 2 diabetes aged over 30 in Shanghai central area, and hyperuricemia was correlated with MS and its components.
【Fund】: 上海市科学技术委员会重大项目(04DZ19504) 国家自然科学基金重点项目(30230380)
【CateGory Index】: R587.1;R589.7
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