Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of Clinical Medicine》 2006-02
Add to Favorite Get Latest Update

Treatment of Eczema and Neurodermatitis with 0.1% Mometasone Furoate Lotion:a Multi-center Clinical Trial

HU Dongyan LI Ming PAN Lin,et al Department of Dermatology,Zhongshan Hospital,Fudan University,Shanghai 200032  
Objective:To observe the clinical efficacy and safety of 0.1% monetasone furoate lotion in the topical treatment of neurodermatitis and eczema. Methods: A randomized double-blind double-simulation parallel controlled clinical trial was conducted. 0. 1% monetasone furoate cream (trade name:Alosonne) was in control. Patients used the cream firstly then the lotion once daily for 4 weeks. Symptom/sign scores were evaluated at the beginning of the treatment and at the 1st.2nd,4th week after the initiation of the treatment. Results: 133 patients with neurodermatitis and 141 patients with eczema were enrolled. There were 137 patients in the treatment group and 138 patients in the control group respectively. All symptom/sign scores and total scores were significantly decreased 1,2 and 4 weeks after the treatment. No statistically significant difference was observed between the two groups. The cure rate and improvement rate in neurodermatitis patients were 59. 09% and 98. 48% in the test group; 71. 21 % and 98. 48% in the control group; respectively. While the cure rate and improvement rate in eczema patients were 49. 30% and 98. 59% ; 58. 57% and 100% in the control group; respectively. No statistically significant difference in efficacy was observed between the two groups. The side effect rate in the test group was 3. 6% ,2. 9% in the control group; respectively. No statistically significant difference in side effect was observed between the two groups. Conclusion:These results suggest that 0. 1 % monetasone furoate lotion is an effective and safe drug in the treatment of neurodermatitis and eczema.
【CateGory Index】: R758.32;R758.23
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 1 Hits
1 YANG Xue-yuan*, HU Zi-jia, BI Zhi-gang, GU Jun, FAN Wei-xin, WANG Se-feng, YU Hao, LOU Dong-hua. *Institute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing 210042,China;Treatment of Eczema and Neurodermatitis with 0.1% Mometasone Furoate Cream: A Multi-Center Clinical Trial[J];Chinese Journal of Dermatology;2005-01
【Co-citations】
Chinese Journal Full-text Database 2 Hits
1 SUN Guang-xia(Outpatient Department,Changzheng Hospital,Second Military Medical University,Shanghai 200003,China);Treatment of Neurodermitis by Lesional Injection of Triamcinolone Acetonide:Observation of Clinical Effect on 36 Cases[J];Nursing Journal of Chinese People's Liberation Army;2009-02
2 Cui Aimin,et al. (Nantong Maternal and Child Health hospital (226006) China);Experimental Observation of Fu Kang Plastics Treating 46 Gravidity Women Suffered from Neurodermitis[J];Journal of Qiqihar Medical College;2006-18
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved