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《Chinese Journal of Clinical Medicine》 2017-03
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Effect of preoperative oral rehydration on general anesthesia induction in patients undergoing gastric cancer surgery based on enhanced recovery after surgery

LIN Jian-da;TIAN Ke;LI Yan;LUO Cong;FAN Jun-yun;QIN Zai-sheng;Department of Anesthesiology,Nanfang Hospital,Southern Medical University;  
Objective:To observe the effect of oral liquid carbohydrates(1,000 mL of liquid carbohydrates 12 hbefore operation,and 500 mL of liquid carbohydrates 2hbefore operation)based on enhanced recovery after surgery(ERAS)on gastric contents reflux aspiration and hemodynamics during general anesthesia induction in patients undergoing gastric cancer surgery.Methods:60patients with ASA gradeⅠtoⅡ and 35-70 years old who underwent laparoscopic radical gastrectomy were randomly divided into two groups:routine fasting group(group G),and preoperative oral liquid carbohydrate group(group E),with 30 cases in each group.Patients in group E took 1 000 mL of liquid carbohydrates 12 hbefore operation,and500 mL of liquid carbohydrates 2hbefore operation.Both groups of patients were given propofol combined with remifentanil target controlled intravenous and injection of cisatracurium in anesthesia induction.HR,BIS,MAP,CO,CI,and SVV were recorded before induction(T0),just before intubation(T_1),1min(T_2),3min(T_3),5min(T_4),10min(T_5),and 20min(T_6)after induction.Gastric contents reflux aspiration during general anesthesia induction and gastric residual liquid capacity were also observed.Results:HR,BIS,MAP,CO,CI of both groups at T_1 were significantly lower than those at T0(P0.05).SVV of group E at T_2-T_6 were lower than those of group G(P0.05),and MAP,CO,and CI of group E at T_1-T_6 were higher than those of group G(P0.05).There was no regurgitation aspiration in both groups during anesthesia induction. There was no significant difference between the two groups in gastric residual liquid capacity.Conclusions:Preoperative oral rehydration(1 000 mL of liquid carbohydrates 12 hbefore operation,and 500 mL of liquid carbohydrates 2hbefore operation)based on ERAS can better maintain hemodynamic stability during induction of general anesthesia in patients undergoing elective gastric cancer surgery,without increasing the gastric residual liquid capacity and the risk of reflux aspiration.
【Fund】: 广东省科技厅科技计划基金(2014A020212170)~~
【CateGory Index】: R614.2;R735.2
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【Citations】
Chinese Journal Full-text Database 2 Hits
1 AO Xiang;HU Bao-ji;XIE Peng-cheng;Department of Anesthesiology,Pudong Hospital,Fudan University;;Research progress in perioperative fluid therapy[J];中国临床医学;2016-05
2 ZHU Yun-he, HU Yu-ping, ZENG Xian-ming, SUN Qian, LIU Jian, LI Wei-yan.Key Laboratory of Anesthesiology of Jiangsu Province; Xuzhou Medical College, Xuzhou 221002, China;The impact of different fluid treatment regiments on hemodynamics during anesthesia induction in patients undergoing selective gastrointestinal surgery[J];临床麻醉学杂志;2012-06
【Co-citations】
Chinese Journal Full-text Database 2 Hits
1 LIN Jian-da;TIAN Ke;LI Yan;LUO Cong;FAN Jun-yun;QIN Zai-sheng;Department of Anesthesiology,Nanfang Hospital,Southern Medical University;;Effect of preoperative oral rehydration on general anesthesia induction in patients undergoing gastric cancer surgery based on enhanced recovery after surgery[J];中国临床医学;2017-03
2 LU Wenbo;YANG Shizhong;SHAO Xuequan;Zhejiang Provincal Corps Jiaxing Hospital of Chinese People′ s Armed Police Force;People′s Hospital of Quzhou City;;Influence on perioperative blood conservation and deep vein thrombosis incidence in perioperative period of total knee arthroplasty on general anesthesia and continuous epidural anesthesia[J];中国医药导报;2013-35
【Secondary Citations】
Chinese Journal Full-text Database 1 Hits
1 XU Yuan,LI Tian-zuo,CHEN Lei,et al.Department of Anesthesiology,Tongren Hospital,Beijing 100730, China;Role of bispectral index monitoring in total intravenous anesthesia[J];临床麻醉学杂志;2010-07
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