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《Chinese Journal of Clinical Pharmacy》 1998-01
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Effects of hemorrheology of domestic and imported ticlopidine-an open paralleled controlled study

Cai Naisheng,Wang Minhua.Zhou Daxing, et al (Cardiology Department,Zhongshan Hospital Affiliated Shanghai Medical University, Shanghai 200032)  
AIM : To evaluate the effect of hemorrheology ,domestic ticlopidine (Lixuda) was compared to imported ticlopidine (Ticlid). METHODS: An open paralleled-controlled trial on 60 subjects with high blood pletelet aggregation who suffered from cardiovascular diseases was carried out. RESULTS: Two drugs can decrease blood fibrinogen, vescosity of blood and vescosity of plasma significantly (P 0. 05 ), but no significances between two drugs(P0. 05). Two drugs can prolong bleeding time and clotting time,but there were no significances between two drugs. The adverse effect rates of domestic and imported ticlopidine were 22-5% and 30% respectively, and no significances between two drugs (P 0.05)). CONCLUSION; It shows that domestic ticlopidine has the same effects on blood pletelet aggregation as imported ticlopidine.
【CateGory Index】: R96
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