STUDIES ON IMMUNOLOGICAL TEST OF VECCINATING COW AND SHEEP WITH ESCHERICHIA COLI K_(99)-F_(41) GENE ENGINEERING SUBUNIT VACCINE
Wang Yujiong; Xu Guizhen ;Lu Yuling(Ningxia Agircultural College)Liu Zi; Xu Chongbo; Feng Shuzhang(Changchun PlA Agriculture and Animal Husbandry UniversityYang Peng; Zhou Jiqing(Milk Cattle Farm of Pingjibao)
pregnant cows and 1225 pregnant sheep were vaccinated with Escherichiacolt K99 -F41gene engineering subnit vaccine and all of those not showed ill reaction,the newborn young stock grew normally. Among 1150 newborn calves which were borne by vaccinated cows, 65 newborn calves were attacked by lax (the percentage was 5. 65%), 12 ill calvesdied (the death rate was 18. 5%). In conparison with contrast group (attack rate was 76.2%, death rate was 59. 4% ),there was a significant difference (P0. 01)between attack rateand death rate of test group and those of contrast group,Among 1226 newborn lambs whichwere born by vaccinated sheep, 54 newborn lambs were attacked by lax(attack rate was 4.4% ), 9 ill lambs died (died rate was 16. 7% ),In comparison with contrast group(attack ratewas 73. 4%,death rate was 22. 3% ),there was a signifcant difference (P0. 01)between at tack rate and death rate of test group and those of contrast group.The result suggested that it was effective and safe to prevent diarrhea of newborn calvesand lambs by inoculating pregnant cows and sheep with k99-F41 gene engineering subunitvaccIne.