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Defibrase VS batroxobin(DF-521)in treating ischemia cerebral vascular disease (ICVD)

GE YuHao Wang zixian Anhui Provincial Hospital Hefei 230001  
Objective TO evaluate the efficacy and safety of defibrase in treatingICVD, Methods Thetreatment group of29 patients were treated with zhaoke defibrase 5BU , iv drip qd for 5d ; The other 27 patients in control group were treated with Batroxobin(DF-521)first dose 10BU, d3 and d5 both with 5BU iv drip. Results The total effective rate was 93. 1% in former group and 96. 3% in latter group(P0. 05) ; The improvements of the hemorrheology parameter between two groups were no significant difference; And notable adverse reaction was not observed Concluston The efficacy and safety of domestic zhaoke defibrase and imported Batroxobin(DF-512) are similar
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