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Influence of Rhizoma Zingiberis Recens on Hair Growth of C57BL/6J

LIU Li,ZHU Hongxia,CHEN Yuyao,YE Wenjun,LIU Qiang(College of Traditional Chinese Medicine,Southern Medical University,Guangzhou 510515,Guangdong,China)  
Objective: To study the effects of Rhizoma Zingiberis Recens on hair growth of C57BL/6J mice.Methods: Different dose of Rhizoma Zingiberis Recens on hairless mice skin was used to investigate the effects of promoting hair growth;influence on hair follicle and melanin were observed through histological examination.Results: The skin color of all groups of Fresh Ginger-treated mice turned from pink to black after 14 days.On day 19,all groups of Fresh Ginger-treated mice's hair were growing.After 29 days,all groups' Fresh Ginger-treated mice overgrew hair.Compared with the mice in the blank control group,Fresh Ginger-treated mice had remarkable difference.In the primary growth and cartage,the auxo-action of Fresh Ginger on hair growth of mice was feeblish than the positive group,but in the atlater stages,the effects were all the same.The pathological section showed that the melanin in the dermis of the treated-mice was increasing,and the drug activated hair follicle's growth,making it turn into period of growth,whereas the blank control group still in the resting phase.Conclusion: Rhizoma Zingiberis Recenshas has significant effect on activating hair growth.
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