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Effects of propolis on kidney in diabetes mellitus rats

HU Fu-liang, XUAN Hong-zhuan, ZHAN Yao-feng(College of Animal Sciences, Zhejiang University, Hangzhou 310029)  
diabetic mellitus SD rats were randomly divided into 6 groups, an d given intragastrically(1)sterile saline(model control group),(2)propolis solut ions extracted by water(low dose), (3) propolis solutions extracted by water ( h igh dose), (4) propolis solutions extracted by ethanol (low dose), (5) propolis solutions extracted by ethanol (high dose), or (6) acarbose (positive control g roup) respectively and treated twice daily continuously for 7 weeks. The serum levels of uric acid , urea and creatinine were determined and comparision betwee n the groups ,and the ratio between kidney weight and body weight was also deter mined . The results showed that propolis could decrease the serum level of uric acid ,urea and creatinine, and could decrease the ratio between kidney weight an d body weight. The results indicate that propolis could protect kidney in diabe tic mellitus
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