Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of Ethnomedicine and Ethnopharmacy》 2009-08
Add to Favorite Get Latest Update

Effects of Dihydromyricetin on the content of ALT,AST,HA,LN,PC-Ⅲ,CⅣ in serums on hepatic fibrosis in rats

KUANG Manyuan,JIA Lei,LUO Mingying(Department of Anatomy Xiangnan Medical College,Chenzhou,423000,China)  
Objective:To observe the effects of dihydromyricetin on the content of ALT,AST,HA,LN,PC-Ⅲ,CⅣ in serums on hepatic fibrosis in rats induced by carbon tetrachloride(CCL4).Methods:Eighty four male SD rats were randomly divided into six groups:normal group,model group,Fufangbiejiaruanganpian group positive,lower,middle and high dosage of dihydromyricetin treatment groups.The hepatic fibrosis rat model was developed by subcutaneous injection of 40%CCL4 for 13 weeks.At the same time of modeling,rats were treated with dihydromyricetin at 25mg/100g,50mg/100g or 100mg/100g.Then the content of ALT,AST,HA,LN,PC-Ⅲ,CⅣ were detected in liver serums.Results:Compared with control group,the content of ALT,AST,HA,LN,PC-Ⅲ,CⅣ in serums of rats of model group all raised markedly(P0.01).Compared with model group,the content of ALT,AST,HA,LN,PC-Ⅲ,CⅣ in serums of rats of Fufangbiejiaruanganpian group positive and lower,middle and high dosage of Dihydromyricetin treatment groups reduced markedly(P0.05).Conclusion:Dihydromyricetin can protect hepatocytes from injury and prevent the progression of hepatic fibrosis in rats.
【CateGory Index】: R285.5
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 6 Hits
1 He Guixia, He Qun, Pei Gang ,Deng Jianqi(College of Pharmacy, Hunan College of TCM, Changsha 410004);Determination of Content of Total Flavononids in the Yaos Ampelosis Grossedetala[J];Hunan Guiding Journal of Traditional Chinese Medicine and Pharmacology;1999-12
2 KUANG Man-yuan,LIU Ying-xia,LI Ying-ju,et al(Department of Pathogenic Medical College of Nanhua University,Hengyang,Hunan 421001,China);Tengcha Flavonoids on Rat Hepatic Fibrosis Induced by Carbon Tetrachloride[J];Journal of Nanhua University(Medical Edition);2008-06
3 LAN Cheng-sheng , LAN Shu-bin (Faculty of Pharmacy of Guangxi traditional Chinese Medical University, Guangxi, Nanning, 530001);Research progress in dihydromyricetin[J];Chinese Journal of Ethnomedicine and Ethnopharmacy;2008-12
4 KUANG Man-yuan~(1,3) WANG Qi-ben~2 LI Ying-ju~3 LI Xiao-fen~3 DENG Peng-cheng~2 LIU Ying-xia~3 (1 Department of Pathogenic Medical College of Nanhua University,Hengyang,421001,China;2 Department of Anatomy Xiangnan Medical College,Chenzhou,423000,China;3 The liver Disease Research Center of the First Affiliated Hospital of Nanhua Universty,Hengyang,421001,China);Preventive Effect and Mechanism of Tengcha Flavonoids on Rat Hepatic Fibrosis[J];Progress in Modern Biomedicine;2008-12
5 Xiong Haoping1,2 He Guoqing1 Yang Weili2 Zhang Yousheng3(1College of Biosystem Engineering and Food Science Zhejiang University Hangzhou 3100292College of Food Science and Technology Hunang Agricultural University Changsha 410128 3The Sericulture Research Institute of Guangdong Academy Science of Agriculture Guangzhou 510641);Analysis on Biochemical Constituents of Ampelopsis Grossedentata[J];Journal of Chinese Institute of Food Science and Technology;2004-03
6 HE Gui xia,PEI Gang ZHOU Tian da,ZHOU Xue xian (Division of Pharmacy,Hunan College of TCM,Changsha 410007,Hunan,China) [;Determination of Total Flavonoids and Dihydromyricetin in Ampelopsis grossedentala (Hand-Mazz) W. T. Wang[J];CHINA JOURNAL OF CHINESE MATERIA MEDICA;2000-07
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 YAN Zan-kai (Department of Chemistry,Hanshan Normal College,Chaozhou,Guangdong 521041);Research Progress on the Methods of Isolation of Dihydromyricetin[J];Journal of Anhui Agricultural Sciences;2008-34
2 XIAO Li-zheng1,GUO Wei1,LIU Su-chun2,YIN Xia1 (1.College of Horticulture and Landscape,Hunan Agricultural University,Changsha 410128;2.College of Food Science and Technology,Hunan Agricultural University,Changsha 410128);A comparative study on antimicrobial activity of tea-extract and dihydromyricetin[J];Journal of Anhui Agricultural University;2008-02
3 ZHANG Cun-li1,ZHU Wei2,WANG Dong-mei1,ZHAN Ying-zhuan1 (1 College of Forestry,Northwest Sci-Tech University of Agriculture and Forestry,Yangling,Shaanxi 712100,China;2 College of Life Science,Northwest Sci-Tech University of Agriculture and Forestry,Yangling,Shaanxi 712100,China);Anti-microbial Activities of the Extracts from Smilax scobinicaulis Roots[J];Acta Botanica Boreali-occidentalia Sinica;2005-12
4 WANG Yu-Tian ZHANG Li-Wei (Institute of Molecular Science,Shanxi University,Taiyuan 030006,P.R.China);Determination of Flavonoids in Antihyperlipidemia Capsule of Yinqi by Differential Spectrophotometry[J];Chinese Journal of Spectroscopy Laboratory;2003-06
5 ZHANG Min LI Guo-Zhang CAO Yong YU Hua-Zhong GONG Zhu-Qong LI Gui(Forest Products Chemical Engineering Key Laboratory of Hunan Province, Jishou University,Zhangjiajie,Hunan 427000,P.R.China);Determination of Total Flavanoid in Leaves of Eucommia Ulmoide by Spectrofluorimetry[J];Chinese Journal of Spectroscopy Laboratory;2005-01
6 ZENG Chun hui,YANG Ke (Guangxi Traditional Chinese Medical University,Nanning 530001);Effect of APS in Ampelopsis grossedentata on Lymphocyte Proliferation in Mice[J];Journal of Guangxi College of T.c.m;2002-01
7 ZHENG Cheng,QI U Ya-r u,ZHAO Yan-hong,FAN Ya-ming(School of Chemistry and Chemical Engineering,Guangzhou University,Guangzhou 510006,China);Microwave extracted dihydromyricetin from Ampelopsis grossedentata in middle industrial scale and the hypoglycemic effects of DMY[J];Journal of Guangzhou University(Natural Science Edition);2007-06
8 Jiang Caiwu,Liang Jing,Qin Jieping,Yang Wei Guangxi TCM University,Nanning,Guangxi,530001;Studies on Preparation of Water-soluble Dihydromyricetin Arginine Compound and Its Characterization and Antineoplastic Activity[J];Guangxi Journal of Traditional Chinese Medicine;2007-02
9 Zheng Zuowen Tan Wei Zhou Yajun Mao Jian Guangxi Traditional Chinese Medical University,Nanning,Guangxi,530001;Inhibitory Effect of Ampelopsis on Proliferation of Human Ovarian Cancer Cells and Malignant Melanoma Cells[J];Guangxi Journal of Traditional Chinese Medicine;2009-01
10 ZHENG Cheng,GAO Xiaoming,YANG Ling, LU Weihua WEi Tengyou ( Department of Biochemical Engineering of Guangzhou University, Guangzhou 510091, China; College of Food and Bioengineering, South China University of Technology, Guangzhou 510640, China; The Industrial Testing and Experimeantal Center, Guangxi University, Nanning 530004, Chian);Extraction of Dihydromyricetin from Ampelopsis through Microwave[J];Guang Zhou Chemical Industry and Technology;2005-02
China Proceedings of conference Full-text Database 1 Hits
1 Yan Zen-kai1, Zhu Hui-ling2, Hu Chun-ju3, Huang Xian-ju2 (1. Department of Chemistry, Hanshan Normal University, Chaozhou 521041; 2. Medical School of Yangtze University, Jingzhou 434000; 3. Department of medical, Hanshan Normal University, Chaozhou 521041);Isolation and Pharmacological Action of Dihydromyricetin[A];[C];2006
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 Zheng Hong Qiang,Liu De Yu Department of Chemistry,Sun Yat sen Medical College,Sun Yat sen University,Guangzhou,Guangdong, 510089,P.R.China;Anti-invasive and Anti-metastatic Effect of Ampelopsin on Melanoma[J];Chinese Journal of Cancer;2003-04
2 Zheng Cheng,Lin Xifan,Lan Guoyong,Yu Lijing,Huang Yan(Guangzhou University Chemistry & Chemical Engineering Department,Guangzhou 510006,China);Extracting the Dihydromyrictin(MAE) from the Ampelopsis by Using Ethanol As a Associated Extracting Methods[J];Guangdong Chemical Industry;2006-10
3 ZHENG Zuo wen1, ZENG Chun hui1, LIN Ying hui2 (1.Faculty of Pharmaceutical Science, Guangxi Traditional Chinese Medical University,Nanning 530001; 2. The No 1 Affiliated Hospital to Guangxi Traditional Chinese Medical University,Nanning 530023);The Protective Effect of APS against Acute Chemical liver Injury of the Mouse[J];Journal of Guangxi College of T.c.m;2002-03
4 Zhong Zhengxian Qin Jieping Chen Xuefen Zhou Guifen (Guangxi Institute of Traditional Medical and Pharmaceutical Sciences,20-1 Donggelu,Nanning,Guangxi,530022,China);Hypoglycemic Effect of Ampelopsin on Diabetic Rats Induced by Steptozotocin[J];GUANGXI SCIENCES;2000-03
5 Zhong Zhengxian Qin Jiepin Zhou Guifen Chen Xuefen (Guangxi Institute of Traditional Medical and Pharmaceutical Sciences, 20 1 Donggelu,Nanning,Guangxi,530022,China);Experimental Research on Total Flavone of Ampelopsis grossedentata from Guangxi in Liver Protection[J];Guangxi Sciences;2002-01
6 LAN Guo-yong,ZHENG Cheng(School of Chemistry,Guangzhou University,Guangzhou 510006,China);Extraction Dihydromyriceti of Ampelopsis on a large Scale by Microwave Assisted Extraction[J];Guangzhou Chemical Industry;2007-01
7 He Guixia, He Qun, Pei Gang ,Deng Jianqi(College of Pharmacy, Hunan College of TCM, Changsha 410004);Determination of Content of Total Flavononids in the Yaos Ampelosis Grossedetala[J];Hunan Guiding Journal of Traditional Chinese Medicine and Pharmacology;1999-12
8 He Guixia, Li Ling, Xiao Jinren, et al (Faculty of Pharmacetics, TCM Univ. of Hunan, Changsha 410007);The therapeutic effects of Tengcha Flavonids on hepatic injury induced by CCl_4 among mice[J];Journal of Hunan Traditional Chinese Medicine University of Hunan;2004-04
9 He Guixia,Pei Gang,Zhou Tianda,et al. (Hunan Traditional Chinese Medicine,Changsha 410007);Structure Identification and Isolation of Myricetin from Ampelopsis grossedentala[J];Primary Journal of Chinese Materia Medica;1999-04
10 LI Wei,NING Zheng-xiang(Food Science and Biotechnology Engineering College South China University of Technology,Guangzhou 510640, China);Study on Countercurrent Extraction of Dihydromyricetin[J];Food Science;2004-11
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved